Recently, high dynamic range (HDR) imaging has received significant attention from research community as well as the industrial companies due to valuable applications of HDR images in better visualization and analysis. However, HDR images need to be converted to low dynamic range (LDR) images for viewing on standard LDR display screens. Several tonemapping operators have been proposed for the conversion, however, so far, no significant works have been reported employing artificial intelligence to achieve better enhancement of the output images. In this paper, we present an optimizationbased approach, to enhance the quality of the tone-mapped LDR images using metaheuristics. More specifically, the optimization process is based on the differential evolution (DE) algorithm which takes tone-mapping function of an existing histogrambased method as initial guess and refines the histogram bins iteratively leading to progressive enhancement of the quality of LDR image. The final results produced by the proposed optimized histogram-based approach (OHbA) showed better performance compared to the existing state-of-the-art tonemapping algorithms.
Objectives: To determine frequency of LA clot resolution in patients with severe MS after three months of anticoagulation. Methodology: A descriptive study was conducted over 6 months from Jul 2018 to Jan 2019 including 49 patients who fulfilled the inclusion criteria and visited Cardiology department, NICVD Hospital-Karachi. After clinical evaluation, warfarin therapy was given for 3 months followed by Transesophageal echocardiography (TEE) to access the resolution of LA thrombus. Chi-square test and Fisher Exact test were used to assess the effect of patient characteristics and echocardiographic findings on the resolution of thrombus. Results: The mean age of the study patients was 47.51±9.93 years. The average mitral valve area (cm2) was observed to be 0.68±0.16, while the average size of left atrial (mm) was 54.38±7.19. At the end of 2 months, TEE showed successful resolution of clot in 11 (22.4%). While by the end of 3 months, only 6 (12.2%) patients showed successful resolution of clot. Conclusion: After 3 months of oral anticoagulation, the LA thrombus resolved in almost 1/4th of the study patients. Successful clot resolution showed positive correlation with history of stroke, hemoptysis and clot mobility and negative correlation with severity of tricuspid regurgitation.
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