Melasma is a commonly seen acquired melanoses and presents as symmetrical dark patches on the sun-exposed areas like the face.Multiple treatment modalities have been tried; however, there is no universally effective cure.The Q-switched Nd:YAG laser is the laser of choice for dealing with dermal and mixed epidermal-dermal pigmented lesions,
Tofacitinib has revolutionized the treatment of numerous dermatological conditions in different age groups. However, evidence for its effectiveness, safety and tolerability in the paediatric population is limited. We performed a literature search, which showed that oral tofacitinib is a reliable option in refractory juvenile dermatomyositis, severe alopecia areata, atopic dermatitis and psoriasis. Topical tofacitinib is an effective option in vitiligo and halo naevus. The risk-benefit ratio should be assessed prior to consideration of this molecule. In this narrative review, we have attempted to present a summary of the evidence of using tofacitinib (oral and topical) in paediatric dermatoses.
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