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The use of ecstasy (MDMA), one of the most popular substances among young people in the context of many leisure and fun activities, is moving from party and recreation circuits to high schools and college dorms, in many cases in combination with alcohol consumption. Bearing in mind the concurrent use of the two drugs and the "gateway" thesis of a progression from legal drugs to illegal ones, a causal(1) model of linkages among sensation seeking, attitudes toward alcohol and ecstasy consumption, and frequency of use was tested using structural equation modeling (SEM). The data were obtained from a sample of 450 high school students ranging in age from 14 to 18 (47% male, 53% female). An additional moderator analysis was performed in order to examine a possible moderating role of sensation seeking in the relationship between attitudes toward consumption and frequency of use of both alcohol and ecstasy. Results were consistent with the hypothesis that positive attitudes toward consumption mediate the effects of sensation seeking on drug use. In addition, whereas our results were coherent with the existence of direct effects of sensation seeking on drug use, these were only found in the case of alcohol consumption. However, a moderating effect of this same variable was observed in the relationship between positive attitudes toward ecstasy consumption and its frequency of use. General and specific clinical implications and limitations of these findings are discussed and future lines of research suggested. .

The authors examined the effects of personality and pregnancy worries on pregnant women's mental and physical health with 154 women in the first half of their gestational period. Self-report questionnaires were used to collect information about control variables, sociodemographic (age, educational level, and work), and pregnancy variables (previous miscarriages, weeks of gestation, and planned pregnancy). Personality was measured using the NEO Five-Factor Inventory, pregnancy worries by the Cambridge Worry Scale, psychiatric clinical symptomatology using the Symptom Checklist-90-R (SCL-90-R), and physical symptomatology with the Nausea and Vomiting in Pregnancy Instrument. Significant relations were observed between pregnancy worries, the traits of agreeableness and neuroticism, and all the SCL-90-R dimensions. The analyses revealed a direct effect of neuroticism and agreeableness on pregnancy worries. Pregnancy worries mediated the effects of both neuroticism and agreeableness on interpersonal sensitivity, hostility, and paranoid ideation. Worries were found not to have mediating effects between personality and somatic symptomatology. These results suggest that neuroticism exerts a negative effect on the psychological health of pregnant women, whereas agreeableness has a positive effect (both as a direct effect and as an indirect effect mediated by pregnancy worries). These findings have important practical implications regarding the planning of health care programs for pregnant women: Specifically, health professionals must take personality into account as a potential determinant of pregnant women's health, not only for the prevention of risks (in the case of neuroticism) but also for promoting health (in the case of agreeableness).

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