Previously unknown dispiropyrrolidines were synthesized by 1,3-dipolar cycloaddition of azomethine ylide to 3-arylmethylidene-3Н-furan-2-ones. The cycloaddition reaction was demonstrated to proceed diastereoselectively through an endo-transition state. Alternative transition states for the reaction are discussed.
The title 1,3‐dipolar cycloaddition procedure leads diastereoselectively to the previously unknown dispiropyrrolidine derivatives (IV) via an endo‐transition state.
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