Organ storage techniques have been under scrutiny to determine the best preservation method, particularly in donation after cardiac death (DCD) kidneys. Conflicting literature on the benefit of pulsatile perfusion (PP) over cold storage (CS) warrants further investigation. We analyzed the risk of developing delayed graft function (DGF) in recipients of DCD and donation after brain death (DBD) kidneys undergoing PP or CS. We stratified on basis of cold ischemic time (CIT) to determine the interaction of preservation techniques, CIT and DCD kidneys on developing DGF. Of 54 136 recipients, 4923 received DCD kidneys of which 3330 (67%) underwent PP. Of 49 213 DBD recipients, 7531 (15%) underwent PP. DCD had a higher risk of DGF versus DBD (adjusted odds ratio, AOR 3.2; 3.0-3.5). PP kidneys had less DGF (AOR 0.59; 0.56-0.63) compared to CS. Interaction models of method by donor type referenced to PP/DBD revealed CS/DBD kidneys had higher DGF (AOR 1.8; 1.7-1.9), whereas CS/DCD kidneys had the highest risk of DGF (AOR 5.01; 4.43-5.67). Even though suggestive for a benefit of PP on DGF, this retrospective analysis cannot address whether this is an intrinsic effect of PP or is associated with the logistics of PP such as discard of DCD kidneys based on pump parameters.

Background: The purpose of this research was to determine the prevalence of hypokalemia among patients undergoing acute [MI] therapy at the Department of Cardiology at HMC Peshawar. Methodology and Location of Study This was a research done at one location only: the Cardiology Division of H.M.C. Methods and materials: this research was carried out at the Cardiology Division at HMC Peshawar between January 1 and June 6, 2021). In all, 414 patients went through the trial's extensive screening (including history taking, routine questions, etc.). An electrocardiogram verified the suspected heart attack. Each patient had 5 mL of venous blood drawn and sent off to the lab to rule out hypokalemia. The same consultant pathologist with at least five years of expertise oversaw all laboratory testing. When the serum potassium level drops below 3.6 mmol/L, a diagnosis of hypokalemia may be made. The mean age of the participants was 63, with a standard deviation of 7.04 years; 240 (or 58%) were men and 174 (or 42%) were women.

Background: Prosthetic valve thrombosis is one of the most well-known life-threatening complications after valve replacement surgery. A poor antithrombotic status causes this thrombotic condition. Objective: The purpose of this study to examine how prosthetic valve thrombosis was treated at our institute. Furthermore assessed were the patients' clinical characteristics. Study design: This observational study was conducted using statistical analyses at the cardiac department of cardiology qazi hussain ahmad medical complex nowshera  from jan 2021 to jan 2022 Material and Methods: this study conducted in the Department  Of Cardiology Noswshera Medical College Nowshera ,Qazi Hussain Medical Complex  Nowshera,kpk The study covered 20 patients who consulted the cardiology clinic between June 2020 and July 2021. The patients who were recently diagnosed with PV thrombosis were selected for further study focused on the inclusion criteria. Each patient's clinical characteristics and demographic profile were noted. In-hospital results were also examined. Results: This observational study was conducted on 20 patients. The majority were female patients (55%) among all patients in this study. Fluoroscopy was used to confirm the diagnosis further.

Background: The Prevalence of central obesity is rising, and with it comes a higher risk of cardiovascular disease. Objectives: The goal is to determine whether or not central obesity is related to cardiovascular disease. Methodology: This research method was placed between January 05, 2021, and December 31, 2021, at the Department of Cardiology at GKMC Sawabi. The Prevalence of central obesity among 480 members of the general public was determined by measuring their waist circumferences. They also had their fasting blood sugar checked and their ability to exercise test. Results: The average age was 54.7011.2, and there were 288 females and 192 males. The female-to-male ratio was 60% to 40%. Men were less likely to have a waist circumference of 85 centimeters or more than women. Higher waist circumference was associated with lower and middle socioeconomic status in both sexes. The chances ratio for men against females varied greatly across age groups, body mass index, and socioeconomic position (as measured by family income). Compared to those of normal weight, those with central obesity were more likely to have dyslipidemia, ischemia, and atherosclerosis in a biochemical study of blood samples. Conclusion: Belly obesity is a major risk factor for cardiovascular disease. Keywords: Relationship, Obesity, Cardiovascular Disease