Prostate cancer (PCa) is the world's second most lethal and hateful disease in people. Even while chemotherapy medications have made considerable progress against cancer disease, the body still has to deal with their toxic side effects. In order to produce anticancer medicines with the lowest cost and treatment time, mostly people are using mechanistic techniques. In addition to chemotherapy advanced treatment techniques are also used in clinical practices, and they have an excellent healing results by enhancing patient survival rates. The social care net faces serious challenges because of the lack and high cost of modern therapeutic techniques. The side effects of chemotherapeutic drugs and expensive advance techniques triggered the patient interest towards phytochemicals drugs which indicate that nature always attracts human to fulfill their medical needs at very low cost.
The pharmaceutical industries are showing strong interest in recent research, which has led to the addition of a quite large number of phyto-medicines in PCa therapeutic practices. Currently, several experimental epidemiological and clinical research reports confirmed that plant bio-actives play a significant role in PCa prevention by using different mechanistic ways such as suppressing adhesion, anti-angiogenesis, pro-apoptosis, anti-proliferation, invasion and migration. This review systematically highlighted various strategies to treat PCa and advances in research by using different bioactive plant extracts and isolated components that have been tested for PCa therapy along with corresponding clinical and epidemiological studies.
Edible oils are among the most crucial nutritional constituents as these are utilized for frying or cuisine. Though, these oils are prone towards oxidative deterioration from manufacturing to transportation due to environmental exposure as well as storage conditions which result in generation of different types of oxidation products. The generation of primary and secondary products result in harmful impacts on human health and may also result in cardiovascular diseases in consumers. The mechanism of oxidative deterioration cannot be assessed easily due to complexity of the reaction under which it may take place. Different types of approaches have been proposed to determine the products generated as a result of oxidation so that safety for their user can be assured. Different types of analytical techniques can be employed in addition to chemical methods so that analysis of oxidative deterioration can be done completely. The proposed study is aimed to assess the oxidative stability of oils in addition to the factors which can influence oxidation of these oils under different conditions. This review also summarize the classical and advanced state of the art analytical techniques which has recently been developed in different possible ways and effectively can be employed for analysis of oxidative deterioration of edible oils. This article possibly will oblige as a reference in the assortment, establishing, and enhancement of approaches for investigating the oxidative stability of edible oil.
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