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Accessibility is essential in Land-Use Transport Interaction (LUTI) framework. For residential location choice in particular, it has always been important at theoretical level. At empirical level, the place of accessibility is doubt in some case studies, considering other location characteristics more important, like the social environment and the neighbourhood amenities. However, this result can be caused by the measurement of accessibility. In view of the wealth of approaches, this paper examines whether different accessibility measures can lead to divergent results. Using a residential location choice model for the Lyon urban area, we test various accessibility indicators and we compare the results. Accessibility is an indispensable variable, whatever is the measure. Without it, the model gives inconsistent results. Complex accessibility measures give better results but simple measures are also relevant for residential location choices modelling. The choice depends heavily on the objectives of the application especially if the model is to be used for simulation.

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