Recurrent implantation failure refers to a failure to achieve a clinical pregnancy after transfer of atleast four good-quality embryos in a minimum of three fresh or frozen cycles in a woman under theage of 40 years. We present this retrospective study, in which we proposed local endometrial injuryfor the management of the uterine factors in the case of 30 couples with recurrent implantationfailure. Our conclusion was that local endometrial injury improved the clinical pregnancy rate forthese couples, especially when the study population met specific criteria.
Recurrent implantation failure is represented by the failure to achieve a clinical pregnancy after transfer of at least 4 good-quality embryos in a minimum of 3 fresh or frozen cycles in a woman under the age of 40 years. One of the recent approaches in studying the window of implantation was building the expression profile of the genes of the endometrial cells. We performed a retrospective study which investigated if endometrial receptivity tests improved the outcomes of IVF procedures in patients with recurrent implantation failure. We enrolled 47 couples with RIF and divided them in 2 groups: the first group of 22 couples performed the ERA test and the embryo transfer according to the result of the test; the second group of 27 couples had the embryo transfer done without the ERA test. Our conclusion was that the ERA test did not improve the outcomes for patients with recurrent implantation failure.
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