A retrospective study of 91 dogs with pemphigus foliaceus was performed. Clinical signs of the disease included crusts (n=79), pustules (n=36), and alopecia (n=33). Lesions were most common on the trunk (n=53), inner pinnae (n=46), face (n=37), and foot pads (n=32). Cytological evaluation revealed acantholytic keratinocytes in 37 of 48 dogs. Results of combination treatment with prednisolone and azathioprine were comparable to results with prednisolone therapy alone. More than half of the dogs achieved remission with appropriate therapy, and another 25% significantly improved.
This study reports the survival to discharge, postdischarge survival, and long-term outcome of dogs following surgical correction of a persistent right aortic arch (PRAA). Information for 52 dogs, 28 dogs, and 23 dogs was available for analysis of survival to discharge, postdischarge survival, and long-term outcome, respectively. Ninety-two percent of dogs survived to the time of discharge and 18% of dogs surviving to discharge were euthanized within 2 mo of surgery. Breed, age at the time of presentation, and gender were not correlated with increased odds of death prior to discharge from the hospital. Long-term outcome for dogs was excellent in 30%, good in 57%, and poor in 13% of dogs. Although this study shows a relatively high mortality rate prior to discharge from the hospital and within 2 mo of surgical treatment, the long-term outcome is good or excellent in 87% of survivors. Dogs frequently display either residual clinical signs or require dietary modification long-term, but owner satisfaction is high.
Tracheal collapse is a progressive airway disease that can ultimately result in complete airway obstruction. Intraluminal tracheal stents are a minimally invasive and viable treatment for tracheal collapse once the disease becomes refractory to medical management. Intraluminal stent size is chosen based on the maximum measured tracheal diameter during maximum inflation. The purpose of this prospective, cross-sectional study was to compare tracheal lumen diameter measurements and subsequent selected stent size using both fluoroscopy and CT and to evaluate inter- and intraobserver variability of the measurements. Seventeen healthy Beagles were anesthetized and imaged with fluoroscopy and CT with positive pressure ventilation to 20 cm H2O. Fluoroscopic and CT maximum tracheal diameters were measured by 3 readers. Three individual measurements were made at 8 pre-determined tracheal sites for dorsoventral (height) and laterolateral (width) dimensions. Tracheal diameters and stent sizes (based on the maximum tracheal diameter + 10%) were analyzed using a linear mixed model. CT tracheal lumen diameters were larger compared to fluoroscopy at all locations. When comparing modalities, fluoroscopic and CT stent sizes were statistically different. Greater overall variation in tracheal diameter measurement (height or width) existed for fluoroscopy compared to CT, both within and among observers. The greater tracheal diameter and lower measurement variability supported the use of CT for appropriate stent selection to minimize complications in veterinary patients.
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