Hipertensi merupakan penyakit kronis yang harus membutuhkan waktu pengobatan yang cukup lama sehingga mempengaruhi kepatuhan minum obat. Ketidakpatuhan dengan program terapi adalah persoalan yang besar pada pasien hipertensi. Ketidaktaatan pasien hipertensi bisa terjadi karena kurangnya pengetahuan serta pemahamannya terkait tata cara pengobatan. Tujuan pemberian edukasi farmasis pada pasien hipertensi peserta Prolanis di Puskesmas Kaliwedi adalah untuk meningkatkan pengetahuan dan kepatuhan minum obat pasien hipertensi dalam menjalani pengobataanya sehingga tujuan dari terapi hipertensi dapat tercapai. Penelitian ini menggunakan metode quasi experiment dengan one group pre-test and post-test designe, pengambilan sampel menggunakan metode total sampling memperoleh responden sebanyak 50 orang. Kesimpulan dalam penelitian ini yaitu adanya pengaruh edukasi farmasis terhadap pengetahuan dan kepatuhan minum obat yang signifikan dari pasien hipertensi peserta Prolanis. Dari hasil uji wilcoxon didapatkan nilai p-value untuk variabel pengetahuan dan kepatuhan adalah 0,000 (p<0,05) yang menunjukkan terdapat perbedaan nilai pengetahuan yang signifikan sebelum dan setelah edukasi farmasis.
Indonesia is a country where people are still productive in consuming herbal medicine. The number of consumers of herbal medicine resulted in some herbal medicine manufacturers adding medicinal chemicals in it. In accordance with BPOM rules that apply a herbal medicine may not contain the slightest BKO. This study aim to analyze the content of mefenamic acid in herbs that circulate around the Sumber Regency market in Cirebon. Mefenamic acid is one of the drugs used to treat various kinds of pain, especially toothache, muscle aches, joint pains and aches when or before menstruation. The method used in this research is descriptive qualitative test using Thin Layer Chromatography (TLC) and quantitative tests using UV-Vis spectrophotometry. In TLC, the initial identification of a compound is based on a comparison of the value of Rf versus standard Rf. Rf values are generally not the same from laboratory to laboratory even at different analysis times in the same laboratory, so it is necessary to consider the use of relative Rf, ie the Rf value of compound stains compared to other compound stains on the same plate. Five of the eight samples found on the market contained mefenamic acid compounds. The samples containing mefenamic acid of found in the code numbers B, C, F, G and H. The highest levels of mefenamic acid were found in the B-1 sample of 0.14%. According to the One Way ANOVA statistical test results obtained a sig value of 0.001 <0.05. This shows the data on the levels of mefenamic acid in a sample of aching rheumatic / rheumatic herbs there are significant differences circulating in the Sumber Regency Cirebon market.
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