Aim: To compare the outcome of operative versus conservative management of humeral shaft fractures. Study design: A longitudinal study Place and Duration: This study was conducted at Civil Hospital Mithi District Tharparkar Pakistan from July 2020 to July 2021. Methodology: The study included 30 patients having humeral shaft fractures who were divided into two groups. One group was managed conservatively whereas the other was managed surgically. The patients were followed up for 1 year and the clinical and radiological examination was performed to assess the complications and clinical outcomes. Results: Most of the patients who have humeral fractures were because of roadside accidents. No significant differences were present in the time of union between both groups, similarly, elbow ROM at the fracture union was also not significantly different. However, malunion was more frequently observed in the conservatively managed group which was 12.7% as compared to the operative group which was 1.3%. Conclusion: No significant difference was observed in reference to the timing of union between the two groups. All humeral fractures need an assessment before opting the conservative or operative management depending upon patient expectations and characteristics of fractures. Keywords: humerus, fracture, operation, conservative management
Aim: To assess the efficiency of intra-articular platelet-rich plasma (PRP) injection in grade I and grade II osteoarthritis in the knee joints Study design: A longitudinal study Place and Duration: This study was conducted at Murshid Hospital and Health Care Center Karachi Pakistan from January 2021 to June 2021. Methodology: The ages of the patients were between 35 years and 65 years. All the patients were diagnosed with osteoarthritis of grade I and grade II. A total of 3 injections of PRP were injected intraarticular in the knees at an interval of 4 weeks. Patients were asked to come for a follow-up in the outpatient department. They were assessed for physical mobility and pain related to arthritis using the WOMAC score. The assessment was done when the treatment was given and after 6 months. Results: A total of 250 patients were considered in the present study. The mean age of the patients was 55.63±5.65 years. The ratio of disease in females to males was 3:1. A total of 178 patients had grade I osteoarthritis and 72 patients had grade II osteoarthritis according to Kellgren–Lawrence classification. A total of 210 patients had reported experiencing symptoms for less than 2 years and the remaining 40 had been experiencing the symptoms for more than 2 years. The mean WOMAC score was 82.9 before the treatment was started and it was 39.15 after 6 months of the treatment. The improvement of WOMAC score was more in the patients having symptoms for less than 2 years. Minor hyperemia was seen in 4 patients and those patients were managed conservatively by ice application and activity limitation. None of the patients showed signs of infection. Conclusion: The intraarticular injection of PRP proved to be beneficial and effective in the treatment of grade I and grade II early osteoarthritis. Keywords: Osteoarthritis, Platelet-rich plasma, PRP, knee joint
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