Copper(ll) complexes of 6-methyl-2-formylpyridine thiosemicarbazone, and its *N-methyl-, *N-ethyl-, 4N-phenyl-, 4N-dimethyl-, 4N-diethyl-, 4N-dipropyl-, 3-pyrrolidinyl, 3-piperidinyl-and 3-hexamethyleneiminylthiosemicarbazone derivatives were prepared and characterized. I.r., electronic and e.s.r, spectra of the complexes, as well as ~H and ~ 3C n.m.r, spectra of the thiosemiearbazones, were obtained. The thiosemicarbazones and their eopper(II) complexes show either modest or no growth inhibitory activity against Aspergillus niger, but the *N-dialkyl-and 3-azaeyclo-derivatives exhibit considerable activity against Paecilomyces variotii.
Copper(II) complexes of 6-methyl-2-acetylpyridine N(4)-substituted thiosemicarbazones, coordinated either as a neutral or a monoanionic ligand, have been prepared and characterized. I.r., electronic and e.p.r, spectra of the complexes, as well as ~H-and ~3C-n.m.r. spectra of the thiosemicarbazones, have been recorded. Both the thiosemicarbazones and their copper(lI) complexes show either modest or no growth inhibitory activity against Aspergillus niger, but the N(4)-dialkyl-and 3-azacycloderivatives, and particularly their copper(II) complexes, have considerable activity against Paecilomyces variotii.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.