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Due to increased population growth, arable land is becoming more and more depleted. Phosphorus is then needed more than ever. Therefore the focus is brought to the possibility of returning to the deposits considered so far without interest (Cao et al. 2019;Chen et al. 2017;Dong et al. 2017;Filippov et al. 2019). Within a major project with the group OCP, this work aims at upgrading low grade phosphates. New beneficiation routes are investigated to selectively separate apatite from gangue minerals, mainly carbonates and quartz. A micro-flotation study was conducted on pure minerals of fluorapatite, calcite and quartz based on mineralogical feature of low grade Moroccan phosphates. Results showed the possibility for a direct flotation. The most potent combinations of reagents were: carboxymethylcellulose and sodium alginate when used with sodium oleate and ATRAC as collectors (Aarab et al, 2020). A scale up of these findings to the mechanical cell fail to obtain the same tendency. An asymmetrical fractional factorial design was used with, as parameters: the type of the collector and depressant, their dosage and conditioning time, flotation time, pH and desliming. Partial matrix results presented in this work confirmed the non-possibility of direct flotation under these conditions, but a reverse flotation is possible. Conclusions will be drawn once the DOE results are completed, considering the possibility of direct and reverse flotation of low grade phosphate ore.

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