The aim of the study is improving the efficiency of cows acute postpartum endometritis treatment by use of the drug Metrolek-O. For the treatment of cows acute postpartum endometritis was used the drug Metrolek-O in the dose of 40, 50 and 60 ml with an interval of 48 hours, intrauterus. For the study of blood counts during the cows treatment of the studied groups, blood was taken before and after clinical diagnosis of healing. Blood was taken from 5 cows from each group of IP-using system «Monojet» from tail vein. It was found that sick animals reduced content in the blood: hemoglobin – 22.80 g/l; erythrocytes – х1012 of 1.05 g/l; segment reflexology point pressure-nuclear neutrophils – was 4.02%; globulins – to 10.97% at simultaneous increase in quantity of leukocytes by 2,94х109 g/l and albumin – to 10.97%. When we use dose of the drug Metrolek-O – 50 ml morphological and biochemical blood parameters had large indicators that correspond to background. Drug Metrolek-O in the dose of 50 ml of the more effective as it provides normalization of the gradient of blood and recovery of animals by anti-inflammatory, antimicrobial, constant and regenerating properties, and increasing the dose to 60 ml ineffective because of the allergic properties of the drug, as evidenced by the increase of eozinophils 1.89%.
The purpose of research is to increase the efficiency of cows reproductive function correction by medicine Metrolag-O. It was conducted the research chlinical gynecologic examination of 4 to 8 day cows after calving. The diagnosis of cows acute postpartum endometritis was established on the basis of clinical exams. From the number of cows, patients with acute endometritis was formed three groups by the principle of analogues (1 experimental, 2 experimental, 3 experimental) of 10 animals each. Studied groups of cows were injected interouterus with the help of syringe with catheter by the drug Metrolek-O with an interval of 48 h until recovery. For experimental group 1 was administered the drug at a dose of 40 ml; 2 of the experimental group in a dose of 50 ml; 3 of the experimental group in a dose of 60 ml. Therapeutic efficacy of the drug Metrolek-O for the treatment of acute postpartum endometritis of cows was determined according to the following criteria: duration of the course of postnatal period, recovery period, frequency of drug use, percent recovery. As a result of the conducted research it was established that the prima version of the drug Metrolek-O in the dose of 50 ml at a multiplicity of the introduction of 4.5 times with an interval of 48 h is more effective than dose administration of 40 and 60 ml. Decrease in therapeutic efficacy of Metrolek-O in the dose of 60 ml is the result of add effects of the drug as an allergen.
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