Introduction: rosacea affects approximately 10% of the world's population. It is a recurrent, inflammatory dermatosis that is difficult to deal with despite treatment. Material and methods: literature review from PubMed databases from 2017-2022. Conclusions: It is very difficult to find the cause of acne lesions. What is certain is that various factors overlap: genetic, environmental, immunological disorders, intestinal abnormalities, dietary factors. New treatments are constantly being sought. The overall health of the organism is very important in maintaining the proper function of every organ, but also of the skin - as a barrier against rosacea.
Introduction and purpose: Alzheimer's disease (AD) belongs to the group of neurodegenerative diseases and is the leading cause of dementia worldwide. Its development includes the impact of genetic, metabolic and environmental factors. Despite high prevalence of Alzheimer’s disease and dynamic development of medical science, there is currently no clinically proven causal treatment. The proposed therapies are only symptomatic. However, there is a wide set of substances known as biomarkers that are detected in the blood or in the cerebrospinal fluid (CSF) in the stages preceding full-blown Alzheimer's disease.Brief description of the state of knowledge: In order to obtain material for CSF examination, a lumbar puncture must be performed. It is an invasive procedure, with the risk of complications such as bleeding into the spinal cord, infection or even nerve damage. Obtaining a blood sample for testing specific indicators is less invasive and more widely available. Currently, the diagnostic significance of commonly known markers arising in the progress of the AD pathological process, such as amyloid β, tau protein and its phosphorylated form or β-secretase, is being investigated. As the knowledge on the pathogenesis of AD grows, further markers such as ubiquitin, micro RNA or plasma neurofilament light are tested.Conclusions: There is a collection of biomarkers that can perform a diagnostic function for Alzheimer's disease. Due to the advantages of blood and plasma testing, basing the diagnosis of early forms of AD on these tests seems to be particularly interesting. However, the use of biomarkers on a global scale requires further research and test standardization, as well as the development of guidelines for their interpretation.
Introduction: The gut microbiota is the microorganisms in the digestive tract. They are mainly bacteria. They play a very important role in maintaining the body's homeostasis. The state of the microbiota is influenced by lifestyle including diet, stress and physical activity. In irritable bowel syndrome, there are disorders in the composition of the intestinal microbiota. It is also associated with a disruption in the proper functioning of the gut-brain axis. Aim: The aim of this study was to review the literature reports on irritable bowel syndrome and the impact of a low FODMAP diet. Methods: Data for the article were retrieved using PubMed setting the time descriptors to 2017-2021. Results and conclusions: Irritable bowel syndrome (IBS) is a chronic functional gastrointestinal disease. It is manifested by chronic abdominal pain , diarrhea or constipation and changes in the frequency of bowel movements. It significantly affects the quality of life of patients. The diagnosis uses the Roman IV criteria. Pharmacological as well as non-pharmacological methods are important in the treatment. A low-FODMAP diet plays a major role. Studies show that its proper use significantly alleviates the symptoms of IBS.
Introduction: On the account of the Covid-19 pandemic, many governments around the world have imposed multiple restrictions on public life to prevent the spread of the coronavirus. Social disruption and forced isolation contributed to increased stress as well as increased use of the Internet.Aim of the study: The aim of the study was to investigate the influence of the Covid-19 pandemic on mental health problems, including Internet addiction, and to link Internet addiction with mental health problems such as anxiety, depression symptoms and insomnia.Material and methods: The data for the article was found using the PubMed and Google Scholar websites.Description of the state of knowledge: Internet addiction (IA) is becoming an increasingly serious problem of the modern world. The problem of Internet abuse is associated with various risk factors that are dependent on gender or family relationships, as well as mental disorders.Many studies have confirmed that the Covid-19 pandemic caused negative mental health effects, contributing to increased anxiety and depression symptoms. To reduce stress, people started using the internet more often. This compensatory mechanism can cause even more mental health problems by increasing anxiety, symptoms of depression and insomnia.Summary: Research by many scientists shows that the Covid-19 pandemic is exacerbating the mental health problems associated with IA. Research shows that during the Covid-19 pandemic, it is especially important to be able to manage stress through non-internet-related activities to help prevent IA.
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