"Supranormal" cardiac function in athletes is due to better endothelial and arterial function, related to lower oxidative stress, with optimized ventriculo-arterial coupling; athlete's heart is purely a physiological phenomenon, associated with "supranormal" cardiac function, and there are no markers of myocardial fibrosis.

The N,N'-(methacryloyloxyethyl triehtoxy silyl propyl carbamoyl-oxyhexyl)-urea hybrid methacrylate for applications in tissue engineering was synthesized and afterwards polymerized by direct laser polymerization using femtosecond laser pulses with the aim of using it for further applications in tissue engineering. The as-obtained scaffolds were modified either by low pressure argon plasma treatment or by using two different proteins (lysozyme, fibrinogen). For improved adhesion, the proteins were deposited by matrix assisted pulsed laser evaporation. The functionalized structures were tested in L929 mouse fibroblasts culture and the cells morphology, proliferation, and attachment were analyzed.

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After gamma irradiation, a radioresistant behaviour in PBMC cultures of MS patients was revealed. This radioresistant behaviour was expressed by lower MN induction in CD4+ lymphocytes and by lower apoptosis induction in G0 PBMC cultures and may point to an adaptive response. The higher radiation response in whole blood cultures compared to PBMC cultures was significantly more pronounced in MS patients, suggesting special characteristics of the whole blood environment associated with this pathology.

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