The findings suggest that Wernicke's encephalopathy is underdiagnosed and undertreated. Our study also highlights the need for clarifying diagnostic criteria, identifying the risk factors for thiamine deficiency, and improving awareness among physicians about diagnosis, prevention, and adequate treatment of Wernicke's encephalopathy in alcohol-dependent and non-alcohol-dependent patients.
Previous studies have shown an association between substance use in the corrections population and, though the overall probation population has been declining, the percentage of women on probation has significantly increased. This study collected data on the factors associated with substance use and criminality among West Texas women who were sentenced to the U.S. Probation and Pretrial Services System (USPPSS). Intake records for USPPSS adult women spanning 3 years were reviewed. Among all age distributions and demographics, alcohol use was found to be prevalent. A significant positive correlation was found between immediate and extended family use of alcohol or drugs. Approximately one third of women reported a lifetime history of psychiatric treatment and three fourths reported a lifetime history of emotional/verbal, physical, and/ or sexual abuse. The significant association with alcohol and substance use among these women should be addressed when determining probation planning and social services. Furthermore, the high incidence of emotional/verbal, physical and/or sexual abuse, and suicidality in this population would recommend an approach that includes provision of adequate mental health services.
Fluoxetine is a selective serotonin reuptake inhibitor (SSRI) that is commonly prescribed for major depressive disorder (MDD). Akathisia is one of the well-recognized extrapyramidal symptoms (EPS) of antipsychotics and antiemetics, but also a rare manifestation of antidepressants. There are various documentations of EPS of antidepressants including acute dystonia, Parkinsonism, and tardive dyskinesia. Akathisia is not only a rare extrapyramidal manifestation of fluoxetine but a frequently unrecognized phenomenon in those using this medication. This case report describes a case of akathisia observed in a 69year-old Caucasian female using fluoxetine. Various factors that may have contributed to the development of akathisia in this patient were also discussed as well as implications for clinical practice and future research.
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