To study volumetric changes in the upper airway in obstructive sleep apnea (OSA) patients after maxillomandibular advancement (MMA) and compare findings to polysomnography (PSG) data of the same patients. Patients and Methods Study consisted of 20 OSA patients (mean age 48 years, range 31-59 years, 1 female, 19 male). Mean SNB and SNA angles before surgery indicated mandibular and maxillary retrognathia. All were treated with MMA including pre-and post-operative orthodontics. Pre-and post-treatment cone-beam computed tomograms (CBCT) were used to measure upper airway volume and PSG data to examine apnea-hypopnea index (AHI), oxygen desaturation index (ODI3/ODI4). In addition, Epworth Sleepiness Scale (ESS), General Health Questionnaire (GHQ-12) and amount of MMA was collected from patient´s files. Results Mean maxillary and mandibular advancement was 4.6±1.9 mm and 9.3±1.7 mm, respectively. Statistically significant increase (mean 64.1%) in the airway volume was found with large individual variation. ODI3/ODI4 and AHI values improved statistically significantly from pre-to post-surgery. ODI3/ODI4 reduced from 12.3±9.8 to 4.0±4.2 and AHI 21.4±13.8 to 5.8±7.2. ESS scores improved (lower scores) post-surgery for majority of patients (n=15) while GHQ-12 scores improved (lower scores) in only six patients. Conclusion Maxillo-mandibular advancement increases upper airway volume and reduces OSA symptoms studied by PSG. MMA can be considered as curative treatment for OSA; however, residual AHI can be found in many patients.
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