Background: Repeated digital vaginal examination during labor may be uncomfortable for women and increases the risk of ascending infection. Transperineal ultrasound can assess fetal head descent, position, and cervical dilatation without these side effects. This study was conducted to evaluate the accuracy of transperineal ultrasound in monitoring labor progress. Results: The study included 40 primigravida women in labor. Fair correlation was found between the assessment of fetal head station by vaginal examination (VE) and fetal head perineal distance (HPD) by transperineal ultrasound (TPUS) (Kendall's tau-b (τ) = − 0.299, 95% CI = − 0.479 to − 0.0863, p value = .0063) (Spearman rho = − .3844, p value = .0143; r 2 = 0.1478). Strong correlation was found between the cervical dilatation assessed by VE and by TPUS (Pearson's r = .8601, 95% CI = 0.7493 to 0.9240, p value < .0001, r 2 = 0.7396). There is moderate agreement between VE and TPUS as regards the assessment of head position on the face-clock [weighted kappa (κ) = .557, 95% CI = .362 to.753]. Conclusion: Transperineal ultrasound can be used as an alternative to repeated digital examination for assessment of labor progress.
Background: In endometriosis, there is a chronic immune and inflammatory reaction. Objective: To study the PCR genetic expression of interleukin 37 in the eutopic and ectopic endometrium of women with endometriosis in comparison with controls. Patient and Methods: Forty-six patients were included in the study. Twenty-three women diagnosed as endometriosis and twenty-three women diagnosed as free of endometriosis were subjected to laparoscopy for any other gynecological cause. Interleukin 37 gene expression was studied in ectopic and eutopic endometrium using polymerase chain reaction. Results: Ectopic endometrium expressed high levels of mRNA compared to eutopic endometrium in endometriosis patients. Eutopic endometrium of endometriosis patients expressed high levels of mRNA compared to eutopic endometrium of controls. Conclusion:The finding of high mRNA produced in endometrial tissue suggests that interleukin 37 may be important in the chronic inflammation occurring during endometriosis.
Background Episiotomy or tearing of perineal tissues during childbirth is associated with significant pain in the postpartum period. Although the use of episiotomy is often debated, it remains the most common surgical procedure experienced by women. Pain from episiotomy is poorly treated, though it may be severe and can result in significant discomfort and interference with basic daily activities and adversely impact motherhood experiences. Local infiltration analgesia is the most commonly used method of analgesia during normal labor. This type of local analgesia is achieved by injecting the analgesic agent into the perineum just before delivery with crowning of the fetal head. It is also widely used just before an episiotomy. This study compares the efficacy and duration of pudendal nerve block versus local infiltration on post episiotomy pain relief. Aim of the Work: This study aims to compare the effect of Pudendal Nerve Block with perineal local infiltration of analgesia in post episiotomy pain relief. Study design:Prospectiverandomizedcontrolledclinicaltrial. Patients & Methods The current study was conducted in Ain Shams University Maternity Hospital in the period between August 2018 and Jan 2019. It included 100 primigravida women in labor meeting inclusion criteria attending the causality of Ain Shams Maternity Hospital. Results Our study showed statistically significant decrease mean of study group compared to control group according VAS score from after 1hr to after 6hrs. Also there was statistically significant decrease in patients' need for analgesia in study group compared to control group from after 1hr to after 6hrs. Patients were asked about episiotomy pain and were advised not to be distracted by pain of uterine contraction or any other pain she complains of as much as possible not to alter the study results Regarding the pudendal nerve block group none of the patients receiving effective bilateral pudendal nerve block asked for analgesia during the first hour post injection. Two patients representing 4.4% of the study group asked for analgesia after two hours post injection, by the 3rd hour 6 patients representing 13.3% of the study group asked for analgesia. After completing 6 hours post injection follow up only 21 patients asked for analgesia representing 46.7% of the study group while 24 patients (53.3%) did not require any analgesia for the first 6 hours after injection of pudendal nerve block Conclusion There is statistically significant decrease in mean VAS in pudendal nerve block compared to local perineal infiltration of analgesia from after 1hr to after 6hrs of injection. Also there is statistically significant decrease in patients' need for analgesia in case of pudendal nerve block compared to local perineal infiltration of analgesia from after 1hr to after 6hrs of injection. There is highly statistically significant increase mean of delivery time after injection (min) in pudendal nerve block compared to local perineal infiltration of analgesia but it has no clinical significance. There are no neonatal side effects or complications of pudendal nerve block.
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