Background: Chronic osteomyelitis is a serious and difficult complication in open fractures, occurring in about 20% of cases. Treatment approach must be multidisciplinary with surgical basis. At the end of the classical eradication of the infection, there is often a large bone defect. Guided tissue regeneration (GTR) with allogeneic platelet gel, autologous cancellous bone graft and resorptive collagen membrane is one of the possibilities how to bridge bone defect.
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