We recommend to perform semiquantitative evaluation of neuroblastoma based on SPECT/CT scans, particularly in patients in clinical stages 3 and 4. It is advisable to include soft tissues in the score assessment, as well, given that only soft tissues may be involved in up to 25.
18F-fluciclovine is a PET radiopharmaceutical used for the detection of recurrent prostate cancer in adult men after primary curative treatment with suspicion of recurrence based on elevated prostate-specific antigen level. Several incidental uptakes of 18F-fluciclovine in other tumour types have been described in the literature so far -in breast cancer, hepatocellular carcinoma, and malignant melanoma. Our case report presents a patient with oncological duplicity (prostate gland carcinoma and newly diagnosed neuroendocrine tumour) and with accumulation of fluciclovine in pathologically proved neuroendocrine tumour, later imagined also by octreotide SPECT/CT. To our knowledge, this is the first case of fluciclovine accumulated in a neuroendocrine tumour described in the literature.In conclusion, incidental FCV uptake in cancer types other than prostate cancer has already been described, with our case report adding to this list. FCV PET is a tool to detect recurrent prostate cancer with rising PSA levels. In our case, the patient had low PSA levels and FCV uptake in metastases which were later proven to be NET.
AcknowledgementWe would like to thank Dr. Pavel Veselý, PhD, clinical oncologist, for his help with the clinical data of the patient.
Statement of EthicsWritten informed consent was obtained from the patient for the publication of this case report and accompanying images.
In this paper, the authors focused on the assessment of the individual methods to prevent coal and gas outbursts. The first part deals with a characteristic of this anomalous phenomenon and some basic methods of coal and gas outburst prevention. The second part presents the economic assessment of the costs necessary to ensure the possible prevention methods in the coalface 080 211 in the locality of the Paskov Mine, Mining Plant 3, OKD as, Czech Republic. In this coalface, a simulation method was used for calculating costs for the drift length of 100 m for the use of various prevention methods (irrigation, relief boreholes, relief blasting). The results show the cost of preventive measures during mining intended to eliminate and protect against the formation of coal and gas outbursts. The measures are compared applying the principle of the decision analysis. Four criteria are used for the mutual comparison of the methods (costs, effort, efficiency, time consumption). The comparison has shown that the optimal method to prevent coal and gas outbursts is irrigation.
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