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Methyldopa reacts with barbituric acid to give a red colour having maximum absorbance at 540 nm. The reaction is selective for methyldopa with 0.0 1 mdml as visual limit of quantitation and provides a basis for a new spectrophotometric determination. The colour reaction obeys Beer's Law from 0.1 mg to 2.5 mg/lO ml

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Introduction: Skin whitening is the act of brightening the skin complexion by using substances that are applied on the skin or administered into the body by other means. The use of skin whitening agents has its drawback in terms of causing harmful effects such as skin disorders like depigmentation, rashes, pimples, discolorations, kidney damaged, cancers, neurological and psychiatric disorders depending on how the agents for skin whitening are used. Objective: The paper examines the knowledge, attitude and practice of skin whitening by university female students in north eastern Nigeria, where some dark skinned women in particular tend to bleach their skin. Method: A cross sectional descriptive study. Results: The awareness level of the students about skin whitening agents and their harmful effects was found to be high among the students and little below, half of them are already users of such agents mainly for beautification. Few of them think the use of skin whitening agents can be addictive and lead to social stigma but they don't believe that the use of such agents should be restricted to medical only. Conclusion: Majority of the female students in the Universities in north-eastern Nigeria bleach their skin with dangerous chemical agents meant for other reasons mainly to attract the opposite sex despite having high knowledge of the harmful effects. Government is highly recommended to take the necessary steps to curtail such menace.

The Archean granitoids of the Aravalli Craton (NW India) are represented by orthogneisses (3.3–2.6 Ga) and undeformed granitoids (c. 2.5 Ga). Here we present whole-rock geochemical (elemental and Nd-isotope) data of the granitoids from the Aravalli Craton with an aim of understanding the evolution of the continental crust during the Archean. These Archean granitoids have been classified into three compositional groups: (1) TTG – tonalite–trondhjemite–granodiorite; (2) t-TTG – transitional TTG; and (3) sanukitoids. Based on the geochemical characteristics, it is proposed that the TTGs have formed from the partial melting of subducting oceanic plateau. The t-TTG formed owing to reworking of an older continental crust (approximately heterogeneous) in response to tectonothermal events in the craton. For the formation of the sanukitoids, a two-stage petrogenetic model is invoked which involves metasomatization of the mantle wedge, followed by slab breakoff and asthenospheric upwelling, which leads to the melting of asthenosphere and the metasomatized mantle wedge. It is also proposed that subducted sediments contributed to the genesis of sanukitoid magma.

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