Methemoglobinemia is a common complication of dapsone poisoning. Its´ treatment usually relies on methylene blue infusion. The aim of this study was to report a case of an acute dapsone poisoning with methemoglobinemia treated only with ascorbic acid and activated charcoal. A 16-year-old female voluntary ingested 3 grams of dapsone in an attempt of suicide and presented with desaturation and tachypnea. Lab findings were compatible with methemoglobinemia. After two days of treatment with ascorbic acid and activated charcoal, we observed the disappearance of desaturation and tachypnea. Methemoglobinemia can be treated with ascorbic acid and activated charcoal in limited resource settings.
Posterior reversible encephalopathy syndrome is a rare clinical and radiological entity which can lead to seizures. Some of its risk factors are hypertension and vasculitis, as in the case of Takayasu Arteritis, a large vessel arteritis which damages the abdominal vasculature. We report the case of a patient who presented in a generalized convulsive status epilepticus secondary to a PRES, which was induced by a renovascular hypertension secondary to Takayasu Arteritis. The aim of this study is to report the case of a rare association of Takayasu Arteritis and PRES, and discuss the timeline of the assessment of our patients condition, which allowed us to start the treatment as quickly as possible.
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