Antimicrobial Dyes Polymers a b s t r a c t Schiff bases and their complexes are versatile compounds synthesized from the condensation of an amino compound with carbonyl compounds and widely used for industrial purposes and also exhibit a broad range of biological activities including antifungal, antibacterial, antimalarial, antiproliferative, anti-inflammatory, antiviral, and antipyretic properties. Many Schiff base complexes show excellent catalytic activity in various reactions and in the presence of moisture. Over the past few years, there have been many reports on their applications in homogeneous and heterogeneous catalysis. The high thermal and moisture stabilities of many Schiff base complexes were useful attributes for their application as catalysts in reactions involving at high temperatures. The activity is usually increased by complexation therefore to understand the properties of both ligands and metal can lead to the synthesis of highly active compounds. The influence of certain metals on the biological activity of these compounds and their intrinsic chemical interest as multidentate ligands has prompted a considerable increase in the study of their coordination behaviour. Development of a new chemotherapeutic Schiff bases and their metal complexes is now attracting the attention of medicinal chemists. This review compiles examples of the most promising applied Schiff bases and their complexes in different areas.
In
the present work, magnesium (Mg) AZ31 alloy was coated with
a multifunctional membrane layer composed of ZnO nanoparticles (NPs)
embedded in a poly(lactic acid) (PLA) matrix. We aimed to produce
a stable coating that would be used to control the degradation rate
of the Mg alloy and promote a local antibacterial activity. ZnO NPs
were dispersed at 5 and 10 wt % in a PLA solution and dip-coated onto
the AZ31 substrate. Surface topography, chemical composition, thickness,
electrochemical corrosion performance, mass variation, antibacterial
activity, adhesion performance, and cytotoxicity of an uncoated control
and coated alloys were investigated. The results indicated that the
incorporation of ZnO NPs at various concentrations affords a dramatic
control over surface topography and degradation rates under in vitro
and in vivo environmental conditions when compared to the uncoated
Mg alloy control. In addition, the results confirmed that the coated
layer exerts antibacterial properties and supports cell growth, indicating
this system may have utility for bone tissue engineering applications.
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