Purpose: To investigate the role of inflammatory markers in predicting the spontaneous passage of ureteral stones.
Methods: We retrospectively reviewed 279 patients with ureteral
stones sized 4–10 mm that were managed conservatively. The patients were divided into two
groups: Group 1 consisted of 137 patients who passed the stone spontaneously; Group 2
comprised 142 patients without spontaneous stone passage. The groups were compared using the
Mann-Whitney U and chi-square tests. In addition, univariate and multivariate analyses were
performed to identify the significance of the parameters.
Results: The mean age of the patients was 41.2 years. The patients in Group 1 had a significantly lower mean stone size, white blood cell count and neutrophil count. In addition, stone location, presence of hydronephrosis and history of urolithiasis were significantly different between the groups. Neutrophil percentage, neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio were insignificantly lower in Group 1. In a multivariate analysis, stone size, distal location and hydronephrosis status significantly predicted the spontaneous stone passage. However, inflammatory markers including white blood cell count, neutrophil count and neutrophil-to-lymphocyte ratio could not determine the likelihood of spontaneous stone passage.
Conclusion: Our results suggest that inflammatory markers are no meaningful parameters for the prediction of spontaneous stone passage.
Benign prostatic hyperplasia (BPH) is one of the most common diseases that affects men (Vuichoud & Loughlin, 2015). The incidence of BPH in men aged 50-60 years is 50% and rises with increasing age (Berry et al., 1984). According to the current European Association of Urology Guidelines, open prostatectomy (OP) or enucleation approaches of the prostate, such as holmium laser/bipolar, are the first choice of surgical treatment in men with a substantially enlarged prostate (>80 ml) (Gravas et al., 2020).
To assess the efficacy and morbidity of the holmium laser enucleation of the prostate and bipolar transurethral enucleation of the prostate in patients with benign prostatic hyperplasia. The study included 60 (55%) and 49 (45%) patients who underwent laser and bipolar enucleation of the prostate respectively. According to the perioperative data, except for length of hospital stay and enucleated prostate weight, all the remaining parameters were similar between the groups. There were significant differences between the preoperative and the postoperative third and 12th month voiding parameters in both groups. In the laser group, the maximum urine flow rate value was better than the bipolar group at the postoperative third and 12th months. However, we did not find any statistically significant difference between the groups in terms of the serum prostate-specific antigen level, International Prostate Symptom Score and postvoid residual urine volume at the postoperative third and 12th months. Our results show that both laser and bipolar techniques are effective minimally invasive surgical treatment options for men with benign prostatic hyperplasia. When compared to bipolar technique, laser technique provides shorter hospital stay, more prostatic tissue enucleation and better maximum urine flow rate values.
Objective:The aim of this study is to evaluate the clinical characteristics and short-and midterm renal functions in patients with acute renal infarction. Methods: The medical records of the patients who were diagnosed with acute renal infarction by computed tomography in our clinic between 2012 and 2019 were retrospectively reviewed. Twenty-four patients who had follow-up data for at least 1 year were included in the study. Clinical, radiological, and laboratory findings of the patients at the time of admission and the results of serum creatinine level and glomerular filtration rate at first month and first year were recorded.
Results:The mean age of the patients was 49.5 ± 20.7 years. In half of the cases, cardiac origin diseases were the underlying risk factor of acute renal infarction. Flank/abdominal pain was the most common presenting symptom. At admission, mean white blood cell count, serum lactate dehydrogenase, serum creatinine, and glomerular filtration rate values were 12 507 ± 6367/μL, 437.4 ± 261 U/L, 1.4 ± 1.9 mg/dL, and 85.3 ± 47.7 mL/min/1.73 m 2 , respectively. Chronic kidney disease developed in 7 patients. Conclusions: Acute renal infarction should be taken into consideration in patients with flank or abdominal pain and increased serum lactate dehydrogenase level. In addition, patients with acute renal infarction are at risk of developing chronic kidney disease.
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