PURPOSE:
To compare centration and functional optical zone (FOZ) after small incision lenticule extraction (SMILE) and femtosecond laser–assisted in situ keratomileusis (LASIK).
METHODS:
In this prospective, randomized, single-masked, paired-eyed, clinical trial, 70 patients received SMILE in one eye and LASIK in the other eye for myopia and myopic astigmatism. FOZ was calculated using custom software on 3-month postoperative refractive power maps (Pentacam HR; Oculus Optikgeräte GmbH, Wetzlar, Germany). Programmed treatment area was defined as the total area of the programmed OZ plus the transition zone. Centration was evaluated by the linear distance between FOZ centroid and the pupil center and the corneal apex.
RESULTS:
The average preoperative spherical equivalent (−5.38 ± 1.65 vs −5.45 ± 1.61 diopters [D]), postoperative spherical equivalent (0.05 ± 0.39 vs 0.06 ± 0.39 D), uncorrected distance visual acuity (0.01 ± 0.13 vs 0.00 ± 0.08 logMAR), and corrected distance visual acuity (−0.07 ± 0.10 vs −0.07 ± 0.10 logMAR) were comparable in SMILE- and LASIK-treated eyes of the 60 patients with complete datasets (
P
> .419). Postoperative increase in spherical aberration was lower in SMILE than in LASIK (0.08 ± 0.16 vs 0.17 ± 0.18 µm,
P
= .002). The FOZ area was significantly larger in SMILE than in LASIK (30.25 ± 3.60 vs 29.21 ± 3.72 mm
2
), despite the smaller programmed OZ diameter (6.48 ± 0.08 vs 6.52 ± 0.11 mm) and smaller programmed treatment area (33.87 ± 0.81 vs 46.30 ± 2.61 mm
2
,
P
< .037). Pupil centration (0.43 ± 0.21 vs 0.41 ± 0.22 mm) and apex centration (0.48 ± 0.24 vs 0.48 ± 0.22 mm) were comparable between SMILE and LASIK (
P
> .694).
CONCLUSIONS:
SMILE created a larger FOZ than LASIK, despite the smaller programmed OZ. This may be due to a difference in the biomechanical response between the two procedures. Visual outcome and centration were comparable between SMILE and LASIK.
[
J Refract Surg
. 2019;35(4):230–237.]
Tissue manipulation may be more uncomfortable during SMILE than LASIK, but not more frightening. Subjective visual symptoms were comparable after 3 months. [J Refract Surg. 2018;34(2):92-99.].
Worldwide, femtosecond Laser Assisted In-situ Keratomileusis (LASIK) is a well known and commonly used refractive technique, although Small Incision Lenticule Extraction (SMILE) has become increasingly popular since it was introduced in 2011. In LASIK, a corneal flap is cut with a microkeratome or femtosecond laser, followed by thinning of the stromal bed with excimer laser ablation. In SMILE, a minor intrastromal lenticule is cut with a femtosecond laser and subsequently removed through a small incision, leaving the anterior and strongest part of the cornea almost intact. Both LASIK and SMILE require cutting of corneal lamellae that may reduce the biomechanical stability of the cornea, with the potential risk of corneal iatrogenic ectasia as a severe complication. However, SMILE preserves the anterior corneal integrity and may, in theory, better preserve the corneal biomechanical strength than LASIK after surgery.A review aimed to examine the current literature that describes and compares the corneal biomechanical properties after Laser Assisted In-situ Keratomileusis (LASIK) and Small Incision Lenticule Extraction (SMILE). A comprehensive search was performed in Pubmed.gov using the following search queries: Corneal biomechanical properties, corneal biomechanics, ocular response analyser, ocular response analyzer, ORA, ex vivo, in vitro, Corvis, Corvis ST, LASIK, and SMILE.
Excimer laser ablation may be feasible for thinning and reshaping of SMILE-derived lenticules before reimplantation or allogenic transplantation. However, controlled lenticule dehydration before ablation is necessary in order to allow stromal thinning.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.