This study explored the factors as determinants to students' achievement in Science with spiral progression approach aimed to know the underlying factors associated with students' level of achievement in science with spiral progression approach; determine if there is any significant relationship among the factors that predict students' performance, and identify which factor best predicts students' performance. A sequential exploratory mixed-method research design was employed in the study. As a result of the analysis, this study suggested three factors that determine students' level achievement in Science: academic causal factor, student causal factor, and learning milieu. These factors were found to be significantly correlated to students' level of achievement and obtained a model that was significantly accountable for the variability in the responses of the factors. Moreover, a very satisfactory was observed on students' level of achievement with significantly varied learning acquisition. Considering the implication of these factors in the implementation of the spiral progression approach is underscored by the need for policy-guidelines revision and review, increase teacher-student support, and learning milieu enhancement.
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