Vertigo-like sensations or apparent perception of movement are reported by some subjects and operators in and around high field whole body magnetic resonance body scanners. Induced currents (which modulate the firing rate of the vestibular hair cell), magneto-hydrodynamics (MDH), and tissue magnetic susceptibility differences have all been proposed as possible mechanisms for this effect. In this article, we examine the theory underlying each of these mechanisms and explore resulting predictions. Experimental evidence is summarised in the following findings: 30% of subjects display a postural sway response at a field-gradient product of 1 T(2)m(-1); a determining factor for experience of vertigo is the total unipolar integrated field change over a period greater than 1 s; the perception of dizziness is not necessarily related to a high value of the rate of change of magnetic field; eight of ten subjects reported sensations ranging from mild to severe when exposed to a magnetic field change of the order of 4.7 T in 1.9 s; no subjects reported any response when exposed to 50 ms pulses of dB/dt of 2 Ts(-1) amplitude. The experimental evidence supports the hypothesis that magnetic-field related vertigo results from both magnetic susceptibility differences between vestibular organs and surrounding fluid, and induced currents acting on the vestibular hair cells. Both mechanisms are consistent with theoretical predictions.

Our findings suggest that depressed individuals differ from healthy controls in the neural substrates involved with processing social information. In depression, the nucleus accumbens and dorsal caudate may underlie abnormalities in processing information linked to the fairness and rewarding aspects of other people's decisions.

BackgroundThere is considerable overlap between left ventricular noncompaction (LVNC) and other cardiomyopathies. LVNC has been reported in up to 40% of the general population, raising questions about whether it is a distinct pathological entity, a remodeling epiphenomenon, or merely an anatomical phenotype.ObjectivesThe authors determined the prevalence and predictors of LVNC in a healthy population using 4 cardiac magnetic resonance imaging diagnostic criteria.MethodsVolunteers >40 years of age (N = 1,651) with no history of cardiovascular disease (CVD), a 10-year risk of CVD < 20%, and a B-type natriuretic peptide level greater than their gender-specific median underwent magnetic resonance imaging scan as part of the TASCFORCE (Tayside Screening for Cardiac Events) study. LVNC ratios were measured on the horizontal and vertical long axis cine sequences. All individuals with a noncompaction ratio of ≥2 underwent short axis systolic and diastolic LVNC ratio measurements, and quantification of noncompacted and compacted myocardial mass ratios. Those who met all 4 criteria were considered to have LVNC.ResultsOf 1,480 participants analyzed, 219 (14.8%) met ≥1 diagnostic criterion for LVNC, 117 (7.9%) met 2 criteria, 63 (4.3%) met 3 criteria, and 19 (1.3%) met all 4 diagnostic criteria. There was no difference in demographic or allometric measures between those with and without LVNC. Long axis noncompaction ratios were the least specific, with current diagnostic criteria positive in 219 (14.8%), whereas the noncompacted to compacted myocardial mass ratio was the most specific, only being met in 61 (4.4%).ConclusionsA significant proportion of an asymptomatic population free from CVD satisfy all currently used cardiac magnetic resonance imaging diagnostic criteria for LVNC, suggesting that those criteria have poor specificity for LVNC, or that LVNC is an anatomical phenotype rather than a distinct cardiomyopathy.