The review addresses one of the important aspects of modern neurosurgery: the repair of various dura mater defects. The optimal material for plastic surgery of the dura mater should meet certain biological, physical and chemical requirements, should not cause serious complications such as liquorrhea, inflammation or brain's lining scars, it should be simple and convenient in use, as well as cost-effective. The present report reviews the concepts and techniques developed in the XIX-XX centuries and also describes the materials used at the present time such as autografts (from patient's own tissues), collagen, and synthetic materials both absorbable and non-absorbable. We analyze a number of domestic and internationally-known implants used in the dura mater plastic repair. The prospects of the new synthetic Russia-made material Reperen for the dura mater plastic surgery are discussed.
The aim of the study was to test an innovative implant made of the urethane bone-replacing material Rekost-M using 3D technologies for customized reconstruction of post-craniotomy skull defects. Materials and Methods. To study the properties of the bone replacement material Rekost-M, physical, mechanical and toxicological tests, as well as preclinical studies on fibroblasts cultures and lab animals (rabbits) were carried out. Clinical evaluation of the developed implant was conducted within a multicenter trial. Results. The replacement of post-craniotomy skull defects with implants made of the bone replacement material Rekost-M represents a reliable method of cranioplasty. Using 3D technology allows for modeling of individual implants of any complexity.
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