The effect of holmium laser enucleation of BPH (HoLEP) on the copulative function of 79 patients was evaluated. The copulative function was assessed by means of the IIEF, AMS scores, ICF scale questionnaires. The bulbocavernous reflex, total and free testosterone and sex hormone-binding globulin were also examined. Patients were examined before surgery, 3 and 6 months later. A decrease in the frequency of erectile dysfunction after 3 and 6 months after surgery was revealed. The frequency of retrograde ejaculation was higher compared with the preoperative value after 3 and 6 months after surgery. An improvement in the reflex and hormonal status of the operated patients was noted. Thus, HoLEP has a dual effect on the state of copulative function in patients with BPH, which results in improved erectile function and increased frequency of retrograde ejaculation.

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Prostate cancer (PCa) is in second place in oncological morbidity in males and is the fifth leading cause of death among the world's population. According to current world statistics, over the past 20 years there has been an increase in primary morbidity, as well as mortality from PCa. The key to diagnosing PCa is a prostate biopsy. Nevertheless, a systemic biopsy under transrectal ultrasound control is the subject of discussion and debate in oncourology, as it has significant drawbacks that affect the qualitative result of the diagnosis of PCa. Given the importance of adequate and staged PCa, various methods of targeted biopsy under magnetic resonance control have been proposed.This review will examine the main features and significance of targeted prostate biopsy, as well as the role of magnetic resonance imaging in the early diagnosis of PCa. The method of targeted biopsy of the prostate gland can improve the detection of PCa in relation to clinically significant forms. In addition, this method is extremely promising and requires further study to further improve the quality of early diagnosis of PCa, especially when selecting patients for radical surgical treatment.

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