Background:Sexually transmitted diseases such as Human Immunodeficiency Virus (HIV) which causes or induces incurable fatal infections have been transmitted through Assisted Reproduction Technology and from infected mothers to the fetus or new born.Aim:The aim of this study is to determine the prevalence of this chronic viral agent among infertile women recruited for Assisted Reproduction Technique programme in Benin City, Nigeria.Materials and Method:Sera (serum) from Five hundred and Ninety infertile women attending Human Reproduction Research Programme/In-vitro fertilization Center at University of Benin Teaching Hospital were screened for the presence of Human Immunodeficiency Virus antibody using three algorithm or techniques of Determine, Unigold and Stat Pack kits. The age range of the infertile women was 20-49 years.Result:28 (4.7%) out of Five Hundred and fifty infertile women recruited for Assisted Reproduction Technique and screened for Human Immunodeficiency Virus antibody were seropositive with increase in prevalence of 10. 0%, 8.5% and 7.5% among infertile women in age groups of (20 – 24), (25 – 29)yrs and (30 – 34)yrs. Chi-square statistical analysis of data shows insignificance in seroprevalence rate in relation to the number of infertile women screened (P > 0.0001) but the screening of these infertile women for the presence Human Immunodeficiency Virus should continue due to the attendant effects.Conclusion:Infertile women who are Human Immunodeficiency Virus carriers give a new dimension to assisted reproductive techniques. This will no doubt help to prevent further spread and adverse pregnancy outcome.
Urogenital tract infection (UTI) contributes to the commonest single defined cause of infertility worldwide. To evaluate the role of urogenital tract infection in male with infertility and its association with sperm quality. Three hundred and twenty three (323) samples from infertile male subject were screened microbiologically for microorganisms associated with urogenital tract infection with seventy-two (72) age-matched male as a control using microbiological standard procedure.164 (50.8 %) infection rate was recorded. The dorminant uropathogen detected or isolated were staphylococcus aureus (14.0 %), Chlamydia trachomatis (11.4 %), Escherichia coli (4.3 %), Micoplasma genitalium (4.0 %) Klebsielli aerogenes (4.0 %). Others were Staphylococus saprophyticus, Pseudomonas aeruginosa, Protein mirabilis with 2.7 % each respectively, Protein vulgaria treponema pallidum (2.1 %), Schistosoma haematobium (0.9 %) Wulchereria Bancrofti (0.3 %), Human immune virus (2.7 %). Semen profile of the male patients with urogenital tract infection had abnormal semen quality in this study P<0.05. Oligospermic infertile male subjects should be screened for urogenital tract infection to further enhance good quality sperms and functions.
Aim: Sexually transmissible diseases such as Hepatitis B virus (HBV) causes or induces incurable often fatal infections have been transmitted through Assisted Reproduction Technology (ART). This study is to determine the seroprevalence of HBV among infertile women recruited for intrauterine insemination (I.U.I). Methodology and Results: A 5mL of blood was collected and serum aspirated. The detection of HBV was carried out using global one-step rapid test kit relative sensitivity of 99% and specific of 97%. Age range of infertile women was 20-49 years. Approximately 30 (5.9%) out of the 512 recruited women were seropositive for HBV with increase in prevalence rate among age group of (25-29 years) and (30-34 years). The rate of infection of HBV was found to be insignificant in this study using chi-square statistical analysis (p > 0.0001). Conclusion, Significance and Impact of Study: Though the rate of the virus infection were statistically insignificant but the screening should be a continuous exercise and be carried out by all fertility center.
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