What are the novel findings of this work?This is the first systematic review to evaluate the prevalence of both isolated adenomyosis and adenomyosis with coexisting endometriosis and/or fibroids in women with subfertility. The pooled prevalence was 10% for isolated adenomyosis, 1% for adenomyosis with coexisting fibroids, 6% for adenomyosis with coexisting endometriosis and 7% for adenomyosis with endometriosis and/or fibroids.
What are the clinical implications of this work?One in 10 women with subfertility have a diagnosis of isolated adenomyosis. However, it is potentially underdiagnosed because of a lack of adherence to standardized diagnostic criteria. Clinicians and researchers should use well-established diagnostic criteria, such as those proposed by the morphological uterus sonographic assessment (MUSA) statement, to report on adenomyosis.
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