The development of cases of COVID-19 (coronavirus disease 2019) in the province Bali to increase until it ranks 10 th in Indonesia. This study aims to determine the characteristics of patients and the description of drug use for COVID-19 patients at Karangasem Hospital Bali for the period April 2020-Aril 2021. This study used a descriptive observational method with a cross-sectional design through a retrospective data search. The number of respondents as a sample was 200 patients with purposive sampling technique. The data collected is in the form of secondary data, which comes from medical records of COVID-19 patients at Karangasem Hospital. The results of the study showed that the most COVID-19 patients in Karangasem RSUD were from adults as many as 109 people (54.5%). Clinical symptoms experienced by all patients were fever with body temperature 38°C for more than 3 days and headache (100%). Patients who had comorbid as many as 196 people (98%) with pneumonia being the highest comorbid as many as 102 people (51%). The length of hospitalization for patients is generally 0-7 days by 69% (138 people). The highest patient status experienced moderate degree of symptoms by 89% (178 people) and severe 11% (22 people). The most drugs given to patients was vitamin C intravenously by 71% (142 people), while antiviral drugs in the form of oseltamivir (tamiflu) became the least by 1% (2 people). The characteristics of moderate-to-severe COVID-19 patients are dominated by male adult patients, have comorbidities (98%), clinical symptoms experienced by all patients are fever for more than 3 days and headache, with hospitalization for more than 3 days. The type of drug that is most often used is for antipyretic analgesics is paracetamol, the type of antibiotic is azithromycin, the type of antiviral is favipiravir, the type of corticosteroid is dexamethasone.
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