D-Penicillamine, previously suspected to have a beneficial effect on the
occurrence of severe retrolental fibroplasia among very low birth weight infants, was tested
to determine the extent to which this drug modifies acute radiosensitivity on 3- to 4-
day-old mice in comparison with adult animals. It was found that the radioprotective effect
of penicillamine, given in doses of 3,000 mg/kg i.p. 60 min before whole-body exposure to
6-10 Gy of 60Co gamma rays, was greater in 3- to 4-day-old mice than in adult animals.
These data seem to be compatible with the view that D-penicillamine, by virtue of its
antioxidant action, may reduce the toxic effects associated with exposure of the newborn
infant to hyperoxia, specifically retrolental fibroplasia and bronchopulmonary dysplasia.
Case report on a child with acute lymphogenous leukemia. Although there was constant hematological remission she developed an isolated leukemic iritis and secondary glaucoma. The clinical picture showed a characteristic stratification of the hyphema. After the patient had remained seated for a prolonged period of time the leukemic cells settled above the erythrocytes, forming a so-called pseudohypopyon, which diagnostically important. Cytologic examination after anterior chamber paracentesis is indispensable in order to establish the etiology of the disease. Isolated leukemic iritis may be the first sign of a relapse and therefore indicate a need to reinstitute induction therapy.
Continuous administration of a local anaesthetic agent via an indwelling catheter into the intraconal space allowed ophthalmic anaesthesia without time restriction. Thus, CRA is a good alternative to general anaesthesia for patients undergoing long-lasting ophthalmic surgery.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations –citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.