We conclude that in subjects being considered with GDx-VCC, the presence of visually significant PCO may introduce artifact as judged by the typical scan score.
Recently there have been several reports of surgical treatments for exuberant blebs related to excessive filtration, including compression sutures/ intra-bleb autologous blood injection, 2 scleral patch grafts 3 and fascia lata patch grafts. 4 These can be used in conjunction with more recognised treatments such as electrocautery and cryoablation. The first operation was thought to have failed in part as a consequence of the patient's warfarin therapy, which had not been adequately reversed. Warfarin disrupts normal coagulation and therefore may have prevented the formation of a satisfactory clot, normally required as the 'scaffold' for the fibrotic process. However, we note that recent literature has questioned the efficacy of autologous blood for this purpose. s We conclude, therefore, that in cases with such exuberant blebs as ours, a more aggressive approach with conjunctival suturing may be required.
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