This report describes the first isolations of Mycoplasma synoviae from the synovial sheaths and joints of commercial chickens affected with synovitis in Australia. Over 4 years 3 separate outbreaks were investigated in which up to 20% of birds exhibited clinical signs of poor growth and "hot foot" syndrome (swollen inflamed footpads). Once an outbreak occurred, chronic infection of the farm usually ensued. Grossly the hocks and footpads were swollen by a purulent exudate and associated inflammatory changes with histological features of a severe acute synovitis. Seroconversion of the flocks occurred at the time of the development of lesions. M. synoviae specific antibodies were demonstrated by ELISA in the joint fluid of affected birds. It is concluded that the cases described are similar to avian infectious synovitis syndrome caused by M. synoviae previously described overseas.
Registration of horse events and movements allowed movement controls to be progressively eased while retaining the ability to trace the movements of large numbers of horses if needed. The number of recorded events, movements and distances travelled confirms the highly mobile nature of the recreational horse industries, helps to explain the rapid and widespread dispersal of the disease before movement restrictions were imposed, and also demonstrates the value of those restrictions as a control measure. The data provide a quantitative snap-shot of horse events and movements, albeit distorted by the prevailing movement restrictions as well as by limitations in the data recording that should be addressed when developing traceability systems for horses in future.
Cytomegaly and intranuclear inclusion bodies were observed in the renal collecting duct epithelium in three of four wild caught platypuses (Ornithorhynchus anatinus) from New South Wales using light and electron microscopy during routine pathological studies. Non-enveloped, spherical virions measuring about 80 nm in diameter were present in the nucleus and cytoplasm of affected cells as well as in the lumen of the renal tubule. A single enveloped virion measuring about 150 nm in diameter was found. There was no serological evidence of infection with cytomegalovirus (AD169 antigen) or adenovirus (mammalian and avian group antigens) in any of the platypuses. Although the identity of the virus was not confirmed, it was probably an adenovirus based on morphological grounds. The infection appeared to have little effect on the host.
Meat chickens housed on a commercial broiler farm in Australia were vaccinated once at 10 to 11 days-of-age by aerosol with live V4 Newcastle disease virus (NDV) vaccine. Groups of vaccinated and unvaccinated birds were flown to Malaysia, where they were challenged with a virulent strain of NDV. Survival rates in vaccinated chickens challenged 7, 14, 21 or 31 d after vaccination were 0.47, 0.77, 0.97 and 0.92, respectively. All unvaccinated chickens died due to Newcastle disease (ND) following challenge. Chickens in Australia and Malaysia were bled and the serums tested for haemagglutination-inhibiting (HI) antibody to NDV. Many vaccinated birds with no detectable antibody, and all birds with a log2 titre of 2 or greater, survived challenge. The results showed that this V4 vaccine induced protective immunity in a significant proportion of chickens within 7 d of mass aerosol vaccination. This early immunity occurred in the absence of detectable circulating HI antibody. Non-HI antibody mediated immunity continued to provide protection up to 31 d after vaccination. Almost all vaccinated birds were protected within 3 w of vaccination. It is concluded that the V4 vaccine is efficacious and could be useful during an outbreak of virulent ND in Australia.
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