This work presents the synthesis of nanostructured TiO2 modified with noble metal nanoparticles (Au, Ag) and lysozyme and coated on titanium foil. Moreover, the specific structural and functional properties of the resulting inorganic and hybrid materials were explored. The purpose of this study was to identify the key parameters for developing engineered coatings on titanium foil appropriate for efficient dental implants with intrinsic antibacterial activity. TiO2 nanoparticles obtained using the sol–gel method were deposited on Ti foil and modified with Au/Ag nanoparticles. Morphological and structural investigations (scanning electron and atomic force microscopies, X-ray diffraction, photoluminescence, and UV–Vis spectroscopies) were carried out for the characterization of the resulting inorganic coatings. In order to modify their antibacterial activity, which is essential for safe dental implants, the following aspects were investigated: (a) singlet oxygen (1O2) generation by inorganic coatings exposed to visible light irradiation; (b) the antibacterial behavior emphasized by titania-based coatings deposited on titanium foil (TiO2/Ti foil; Au–TiO2/Ti foil, Ag–TiO2/Ti foil); (c) the lysozyme bioactivity on the microbial substrate (Micrococcus lysodeicticus) after its adsorption on inorganic surfaces (Lys/TiO2/Ti foil; Lys/Au–TiO2/Ti foil, Lys/Ag–TiO2/Ti foil); (d) the enzymatic activity of the above-mentioned hybrids materials for the hydrolysis reaction of a synthetic organic substrate usually used for monitoring the lysozyme biocatalytic activity, namely, 4-Methylumbelliferyl β-D-N,N′,N″-triacetylchitotrioside [4-MU-β- (GlcNAc)3]. This was evaluated by identifying the presence of a fluorescent reaction product, 7-hydroxy-4-metyl coumarin (4-methylumbelliferone).
We propose that through the presented study, to strengthen the value of the pre-excision digital dermatoscopy by emphasizing its accuracy compared to the histopathological examination in the diagnosis and treatment of precancerous lesions of the skin for which the histopathological examination of certainty can only be performed after post-excision.
Ultrasonographic evaluation of the hysterorrhaphy scar is an extremely important element in current obstetrical practice, especially in patients who still want a future pregnancy. The purpose of our study was to evaluate the ultrasound findings of the cesarean scar in the third trimester of pregnancy that can reduce the life-threatening emergencies caused by repeated cesarean section such as uterine rupture of abnormal placental adhesions. We conducted a prospective study that included patients who gave birth by caesarean section and presented at a subsequent pregnancy to be monitored during pregnancy. The study was realized during 2016-2020at the Bucur Maternity Hospital, 'Saint John', Bucharest. A number of 57 patients were included in the analyzed group. A number of 12 pregnant women (21%) monitored both in weeks 30-34 and intraoperatively presented contractions and areas of dehiscence, while 30 (52.6%) pregnant women showed neither contractions nor areas of dehiscence. Women with contractions had an average scar thickness measured in the third trimester of 3.81 mm (SD 1.62, CI: [3.32; 4.30]), and those without contractions a thickness of 4.58 mm (SD 1.25, CI: [3.78; 5.37]. Intraoperatively we identified 3 cases with incomplete uterine rupture. Those cases were previously diagnosed with hysterorraphy scar between 0.15-0.5 cm. The repeated ultrasound evaluation of the cesarean scar is a good predictive factor for the intraoperative quality of the cesarean scar. With the third trimester ultrasound measurement of the uterine scar thickness, the uterine rupture may be avoided.
The authors present a retrospective study over a period of 18 years on electrocutions that were included electrocutions through direct contact (as the clinical presentation) or that were produced by high voltage or low voltage, which aims at extracting conclusions prognostic and therapeutic nature and especially the final therapeutic results, the study concluded that even electrocutions is decreases incidence, mortality of electrocutions with high voltage remains strong.
The purpose of this paper is highlighting the treatment used for patients with skin tumours in the middle third of the face. Fear of a malign skin disease have been rising public awareness of the danger of exposure to sunlight. The probability of developing a skin tumours increases with age. Non melanocytic skin cancers are currently the most common types of cancers in Caucasians; their incidence has steadily increased worldwide in recent decades in the context of actinic aggression and increased exposure to other carcinogens, with geographic variations depending on climate, sun exposure and skin phototype. Knowing the most common forms of benign and malignant skin tumours is crucial for a proper evaluation and therapeutic management. To restore the defects resulting from excision of different types of skin tumour, were used various surgical procedures. The choice of reconstruction method was done according to the need of each patient, considering the location, size and defect results as well as medical history and level of cooperation with each patient.
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