We propose a method for visualizing the mechanical properties of tissue based on the use of periodic mechanical compression in conjunction with phase-contrast MR imaging. A specialized mechanical transducer was used to provide programmable compression pulses to the surface of compliant phantoms. These compression pulses were synchronized to a spin-echo sequence with motion-sensitizing gradients to generate phase information reflecting spin displacement throughout the phantom. This sequence was tested with two agarose gel phantoms. The first was a cylinder containing three parallel layers of varying compliance and the second was composed of a semirigid sphere suspended in a uniform layer of decreased elastic modulus. Images showed complex patterns of motion throughout the phantom, which correlated with expected motion behavior of the phantom structures. This indicates that the biomechanical properties of tissues may be elucidated through the use of motion-sensitized MR imaging and suggests that a form of image contrast relating to tissue elasticity may be feasible.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.