Background
To apply transcranial electrical stimulation (tES) to the motor cortex, motor hotspots are generally identified using motor evoked potentials by transcranial magnetic stimulation (TMS). The objective of this study is to validate the feasibility of a novel electroencephalography (EEG)-based motor-hotspot-identification approach using a machine learning technique as a potential alternative to TMS.
Methods
EEG data were measured using 63 channels from thirty subjects as they performed a simple finger tapping task. Power spectral densities of the EEG data were extracted from six frequency bands (delta, theta, alpha, beta, gamma, and full) and were independently used to train and test an artificial neural network for motor hotspot identification. The 3D coordinate information of individual motor hotspots identified by TMS were quantitatively compared with those estimated by our EEG-based motor-hotspot-identification approach to assess its feasibility.
Results
The minimum mean error distance between the motor hotspot locations identified by TMS and our proposed motor-hotspot-identification approach was 0.22 ± 0.03 cm, demonstrating the proof-of-concept of our proposed EEG-based approach. A mean error distance of 1.32 ± 0.15 cm was measured when using only nine channels attached to the middle of the motor cortex, showing the possibility of practically using the proposed motor-hotspot-identification approach based on a relatively small number of EEG channels.
Conclusion
We demonstrated the feasibility of our novel EEG-based motor-hotspot-identification method. It is expected that our approach can be used as an alternative to TMS for motor hotspot identification. In particular, its usability would significantly increase when using a recently developed portable tES device integrated with an EEG device.
Colorimetric paper sensors have been used in various fields for their convenience and intuitive manner. However, these sensors show low accuracy in practical use because it is difficult to distinguish...
Objectives: The purpose of this study is to report effectiveness of MY1-Hwan(MYH) on wart patients. Methods: Seven wart patients who wanted to treat wart with Korean medicine took MYH 2~3 times a day for 2~4 months without external treatments. Results: Nodules or papules of wart were vanished from seven patients' lesion. Specific side effect was not shown. Conclusions: MYH was effective to treat seven wart cases. However, seven cases are not enough to figure out the various effects of MYH and the effectiveness on other kind of wart. So follow-up studies are needed based on this study.
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