BACKGROUND/OBJECTIVESRecent studies showed vitamin D deficiency is linked to chronic diseases in addition to skeletal metabolism which could threaten the elderly. We analyzed health conditions and socio-demographic factors associated with vitamin D deficiency in community dwelling people aged 65 years and older.SUBJECTS/METHODData from the Korea National Health and Nutrition Examination Survey (KNHANES) 2010 to 2012 were obtained. A total of 2,687 subjects aged 65 years and older were participated. The cutoff value of the Vitamin D deficiency was considered as serum 25-hydroxyvitamin D [25(OH)D] ≤ 20 ng/mL (50 nmol/L).RESULTSThe overall prevalence rate of vitamin D deficiency in the elderly was 62.1%. The factors such as female, obesity, metabolic syndrome, current smoker, and skipping breakfast were positively associated with vitamin D deficiency, but high intensity of physical activity and more than 9 hours of sleep duration were negatively associated with vitamin D deficiency (all P < 0.05).CONCLUSIONSIt is important that health professions know that the factors proved in this study are connected to vitamin D deficiency thus provide information and intervention strategies of vitamin D deficiency to old aged people.
Background
With the prevalence of non-alcoholic fatty liver disease (NAFLD) increasing worldwide, many noninvasive techniques have been used to improve its diagnosis. Recently, the serum uric acid/creatinine (sUA/sCr) ratio was identified as an indicator of fatty liver disease. Therefore, we examined the relationship between sUA/sCr levels and ultrasound-diagnosed NAFLD in Korean adults.
Methods
This study included 16,666 20-year-olds or older who received health checkups at a university hospital’s health promotion center from January to December 2021. Among them, 11,791 non-patients with and without NAFLD were analyzed, excluding those without abdominal ultrasound, those without data on fatty liver, cancer, or chronic kidney disease severity, those with a history of alcohol abuse, and those with serum hs-CRP <5 mg/L. The odds ratio (OR) and 95% confidence interval (CI) of the sUA/sCr ratio according to the presence or absence of fatty liver disease and severity were calculated after correcting for confounding variables using logistic regression analysis. The receiver operating characteristic (ROC) curve and area under the curve (AUC) of the sUA/sCr ratio confirmed and compared the sensitivity and specificity of NAFLD and serum uric acid.
Results
sUA/sCr increased with fatty liver severity, and the post-correction OR in the NAFLD group was 1.183 (95% CI: 1.137–1.231) compared to the group without NAFLD. Concerning the fatty liver severity, the post-correction OR in the mild NAFLD group increased to 1.147 (95% CI: 1.099–1.196), and that in the moderate-to-severe NAFLD group increased to 1.275 (95% CI: 1.212–1.341) compared to the group without NAFLD. The sensitivity of sUA/sCr to fatty liver severity was 57.9% for the non-NAFLD group, 56.7% for the mild NAFLD group, and 59.0% for the moderate-to-severe NAFLD group; the specificity of sUA/sCr to fatty liver severity 61.4% for the non-NAFLD group, 57.3% for the mild NAFLD group, and 65.2% for the moderate-to-severe NAFLD group.
Conclusion
NAFLD severity is associated with sUA/sCR.
Background: Obesity and Central obesity increases the risk of cardiovascular disease (CVD). Recent studies have shown that normal weight central obesity (NWCO) is associated with CVD risk factors and suggested that the waist-to-height ratio (WHtR) is effective predictive index for CVD. The purpose of this study was to examine the association between NWCO, classified using body mass index (BMI) and WHtR, and CVD risk factors in middle-aged Korean men.
Methods:The subjects for this cross-sectional study included 11,917 males aged 40-64 years who visited the hospital for a health check-up. Anthropometric measurements and biochemical studies were conducted. The subjects were categorized into the following four groups using BMI and WHtR: normal weight (BMI 18.5-24.9 kg/m 2 ) and no central obesity (WHtR <0.5) (NW), normal weight and central obesity (WHtR ≥0.5) (NWCO), obesity (BMI ≥25 kg/m 2 ) and no central obesity (OB), and obesity and central obesity (OBCO). A logistic regression model was used to calculate the odds ratio and 95% confidence intervals (CI) for CVD risk factors such as hypertension, dyslipidemia, and diabetes.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.