This study analyzed the concentration of the heavy metals(Cd, Hg, iAs) of urine(n=576) from May, 2007 to Oct 2007. The subject was residents in G, Y, H industrial area, Jeollanam-do, in which exposure due to the adjacency of the industrial complex. As to the heavy metal concentration in the urine of the residents in the whole exposed region and the comparing region, the content of cadmium, mercury, and inorganic arsenic in the exposed region group were 1.23, 1.85, and 8.80 µg/g_ct respectively, and those of the comparing region group were 1.87, 2.00, and 8.93 µg/g_ct respectively, which indicates that the concentration of the comparing group was higher than that of the exposed group. The heavy metal concentration for each age group increased in proportion to age except those under 10 for some substances(p<0.01). As to geometric mean concentration cadmium and inorganic arsenic in urine according to the smoking history of the subject, the concentration of the smoking group and the non-smoking group were 1.65 µg/g_ct and 9.13 µg/g_ct respectively, while those of the non-smoking group were 1.47 µg/g_ct and 8.91 µg/g_ct respectively, which indicates that the former is higher than the latter. As to the inorganic arsenic concentration in urine according to the food preference, in order of vegetable, fish, and meat showed high concentration (p<0.01). To clarify the factors affecting the heavy metal concentration in urine among the subjects, the multiple regression analysis was conducted. As a result, it turned out that as to cadmium content in urine, gender, age, drinking, and smoking have influence on the subjects, with explanatory adequacy of 37.5 %.
BackgroundThe prevalence rate of allergic disease, one of chronic diseases, has been recently increased due to changes of life style and numerous environmental factors. In May 2007, the Ministry of Health and Welfare of Korea established the comprehensive countermeasures to prevent and control asthma and allergic disease in Korea and has pushed ahead with this project related associations and academic experts together.MethodsTo improve the quality of life, reduce social and economic burden through getting over allergic diseases, the evidence based healthcare policy should be established about prevention and control of allergic diseases ; 1) Campaign & education 2) Proper treatment & control 3) Construction of environment friendly living 4) Construction of investigation, monitoring and alert systems 5) Support the disadvantaged patients.ResultsThis project has moved ahead according to each 5 major program ; 1) Establish and provide guideline for prevention & control, promote prevention & control measures by cooperating with the private sector, operate an education & information center for asthma and allergic disease, 2) Provide & educate standard treatment guidelines, program development for a patient's self-treatment & control, 3) Create asthma and allergic disease friendly school, improve the living environment to control the trigger of asthma and allergic disease, 4) Establish an surveillance and monitoring system for asthma and allergic disease, study on asthma & allergic diseases; cohort study, develop and forecast an asthma index, 5) Support the patients of the disadvantaged with treatment, improve the living environment of the disadvantaged patientsConclusionsWe expect that evidence based healthcare policy about prevention and control of allergic diseases would improve the quality of life by reduction inducing factor for allergic diseases, and minimize the recurrence and aggravation by realization of the proper treatment and control the trigger for asthma and allergic diseases.
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