The mechanism of action, leakage of cytochrome c from mitochondria into cytosol, for the antineoplastic compound glyfoline was examined. Additionally, our current studies revealed that glyfoline induced apoptotic changes and arrested cell cycle procession at the G2/M phase in nasopharyngeal carcinoma (NPC). A reverse transcriptase polymerase chain reaction (RT-PCR) showed no specific changes of apoptosis-related gene expression (i. e., bax, ICE-alpha,beta, bcl-2, and c-myc). However, no similar changes were detected in fibroblasts and peripheral lymphocytes after glyfoline treatment suggesting that glyfoline has a higher affinity for tumor cells than for normal cells.
In the present study, the MWNT/epoxy composites are prepared with three weight percentages (0.0, 0.3, and 0.5%) of multiwall carbon nanotube (MWNT). The temporal response of multi-wall carbon nanotube (MWNT)/epoxy composite with different wt% of multi-wall carbon nanotube (MWNT) is measured by experiment. Also, a cavity-type measuring system is designed to experimentally measure the surface temperatures and obtain the thermal conductivity of these composites at different heating rates. It is found that the responses of the 0.3 and 0.5% weight percentage of multi-wall carbon nanotube (MWNT)/epoxy composites are found to be about 25 and 47.8%, respectively, faster than that of the pure epoxy resin. Both the responding characteristics and the variation trends of the measured surface temperatures of these composites can be well predicted by the lumped-heat capacity model. Besides, the higher the weight percentage (wt%) of multi-wall carbon nanotube (MWNT) in the composite, the larger is the thermal conductivity. Relative to the pure epoxy, the thermal conductivities for the composites with 0.3 and 0.5% of multi-wall carbon nanotube (MWNT) increase by 15.9 and 44.9%, respectively. For the weight percentages studied, the thermal conductivity of these composites is found to increase mildly at low heating rates; however, it remains nearly constant at high heating rates
This study measures the thermal conductivity of the MWNT/epoxy bulk composite material to enhance the heat transfer rates of the high power LED device. In this study, three different weight percentages (0.0 wt%, 0.3 wt% and 0.5 wt%) of MWNT/Epoxy composite and five different heat generating rates were employed for the investigation. The case of pure epoxy resins (0.0 wt%) was used as a reference. The responding time and the thermal conductivity of the composites were evaluated. The results show that the response is the fastest for composite with 0.5 wt% MWNT among three composites studied herein. The responses of the 0.3%wt and 0.5%wt composite are increased by 14.3%∼26.7% relative to that of the pure epoxy. Compare with that of the pure epoxy, the thermal conductivities for the cases with 0.3 wt% and 0.5 wt% MWNT/epoxy composite are increased by 15.9%∼44.9%. Further, the thermal conductivity does not vary with temperature for the temperature range studied herein. In the present study, the thermal conductivity of the composite material is found to increase mildly with the increasing heat generation rate.
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