Introduction: The use of medications during pregnancy has increased in the recent years. Some congenital anomalies, birth defects, and miscarriages have been found to be preceded by some medications use during pregnancy. The use of herbal medicines is not yet proved to be safe during pregnancy, since some herbs showed increased risk of certain congenital malformations. Aim: This study assesses the pregnant women perception, beliefs, and attitude toward medication and natural products use and their influencers during pregnancy. Methodology: This is a cross-sectional study targeting women in Alahsa, Saudi Arabia. More than 300 women have responded to a pretested questionnaire collecting their sociodemographic, perception and attitude toward medication and natural product. The data were analyzed using SPSS Statistics under the supervision of a statistician. Results: This study involved 184 participants, 29.2% of pregnant women avoided using prescribed medications, 40.7% non-prescribed, and 33.3% natural products during pregnancy. Paracetamol was on the top of the avoided medications, and herbals were on the top of the avoided natural products. The most common reason for avoidance was fearing of its effect on fetus. More than half of the participants always looked for the product safeness. Pain killers, antibiotics, cinnamon, and pineapple are the most commonly believed products to be harmful during pregnancy. 1 st trimester is believed to be the critical period in which medications and herbals should be avoided. Conclusion: Pregnant women should be educated more about unsafe products during pregnancy. Women's beliefs about natural products need further exploration because of lack of evidence.

Eating habits have strong relationship with nutritional status of any person. Modification of these habits in the adolescent period can prevent malnutrition resulting in prevention of many non-communicable diseases. Additionally, with best eating habits female doctors can be a role model for their patients.Objectives: This study was designed to access the dietary habits, nutritional status and their association in young adolescent female medical students.Methodology: A cross sectional descriptive study was carried out in Medical College of Lahore. A total of 114 female students from 1st year and 2nd year were selected. Their socio-demographic characteristics, dietary habits and nutritional status were assessed through a questionnaire. Hemoglobin levels were measured by Sysmex while mid upper arm circumference and (MUAC) and body mass index (BMI) were measured with the help of measuring tape and weighing machine, respectively. Results: Mean age of the students was 19.5 ± 2.1. All the participants were unmarried, 108 (94.7%) liked traditional food, and 84 (73.3%) had a habit of daily breakfast intake. Most of the students (n=73, 64%) were consuming fast/junk food while 81(71.1%) of the students used to take meat and meat products three times a week. A total of 42 respondents (36.8%) were underweight while 41 (36%) were anemic. Positive association was found between eating habits and hemoglobin levels (p = 0.001). Relationship between regular intake of breakfast with BMI and MUAC was also positive (p = 0.003 and 0.02, respectively). Conclusion: It is concluded that eating habits affect the nutritional status of adolescent females, while skipping breakfast is associated with anemia.

The concerning rise in emergence and prevalence of resistant strains to drugs of M. tuberculosis has ,the prompted researchers to look for new and effective treatments. With this motive, biscoumarins were identified as the lead molecules on a whole-cell-based screening of several less explored low molecular weight bioactive compounds against M. tuberculosis strains. Among the screened biscoumarins, the highest dock score derivatives were synthesized (a-h) using a programmable microwave synthesizer for better yields and reaction control. The synthesized derivatives were evaluated against H37Rv, H37Ra, M. smegmatis, an MDR surrogate model, and other bacterial strains for the structure-activity response. Assessment of the synthesized library against mycobacterial strains led to the identification of compounds (f and d) as lead anti-tuberculosis agents. Compounds (f and d) exhibited less toxicity against human cell lines. At the same time, it displayed enjoyable activity wherein MIC concentrations were observed to be 16- and 32 µg/mL against the susceptible H37Rv, and H37Ra strains of M. tuberculosis and MIC value of 128 µg/mL for M. smegmatis, respectively. For mechanistic insights and identification of drug binding targets, molecular docking and dynamic simulations were employed for a panel of 16 mycobacterial enzymes essential for mycobacterial growth and survival. These in silico studies revealed the DprE1 enzyme as a druggable target for the anti-tuberculosis activity of the selected biscoumarins derivatives. Further investigation is underway in our laboratory, leading to its development as an anti-tuberculosis drug (animal model studies).

Background: Mostly, woman needs care during some periods of her life including the purpureum. It is a period that starts after delivery of placenta and last for the following 6 weeks. Her health can be improved for the rest of her life with proper care and nutrition during this period. Aim: This study aims to explore different dietary and behavioral customs among women in eastern region in KSA and how it will affect their health. Methods: A crosssectional study was carried out in the eastern province of Saudi Arabia.Women who experienced surgical or medical difficulties throughout their period were excluded. Using a pre-constructed validated questionnaire to interviewed eligible women. Data collected included demographical data, dietary and behavioral practices and the source of the knowledge and practices and the social support. Results: The study questionnaire was completed by 459 females in total. Females' median ages were 26.7, 13.9 years, with ages ranging from 18 to more than 35 years. Their family's elderly female members (47.1%) were the most often cited information source, followed by health education initiatives (22.2%). 95.9% of the female participants-a total of 440-said they had assistance from their friends and family after giving birth.In 405 (92%), both the husband and the mother supplied support, followed by the husband by himself (38%; 167) and the housemaid (21.4%; 94). Conclusion:In conclusion, the findings in the study showed that most study females had received mistaken advice against adopting several healthy behaviors and eating routines during the postpartum period.