The VEMP responses were significantly different between the stimuli of STB and click, and the norms of different stimuli should be established for clinical interpretations. For clinical diagnosis using VEMP, we recommend STB stimuli because the latencies and amplitudes of click were significantly different among several labs, including ours.
After surgery, the 500 Hz air-bone gap (ABG) decreased significantly and the VEMP response rate increased significantly from 41.7% to 66.7% (p<0.05, bi-test). However, both the preoperative and postoperative p13 latencies were significantly longer than those of the healthy controls (p<0.05, Wilcoxon rank-sum test). In the 18 patients whose 500 Hz ABG did not improve with surgery, the p13 latencies were significantly shorter postoperatively (p<0.05, sign test), and the response rate also improved significantly from 44.4% (8/18) to 77.8% (14/18) (p<0.05, bi-test).
The responses of ocular vestibular evoked myogenic potential (oVEMP) vary significantly with the type and setting of the stimuli. This work was to investigate the effects of different ramp time and plateau time on oVEMP latency and amplitude. Twenty-two healthy volunteers aged from 20 years to 39 years were enrolled. The oVEMPs were acquired with the eyes upwards-gaze 30 degree above the head, and the sound stimuli included 0.1-ms click, and 500-Hz short tone burst (STB) of rise-plateau-fall time of 0.5-2-0.5 ms, 0.5-4-0.5 ms, 2-2-2 ms, and 2-4-2 ms. The response rate of click oVEMP (66%) was lower than STB oVEMP (100%). The click oVEMP amplitude was significantly smaller (p < 0.01, one-way ANOVA and post-hoc Scheffe procedure). The latency n1 increased by 1.4 ms as the rise/fall time shifted from 0.5 ms to 2 ms for STB stimuli. However, the latency and amplitude did not show significant difference between the STB stimuli with different plateau times. The lower amplitude and response rate for click oVEMP were associated with its lower mechanical energy of click, especially the energy from 500 to 1000 Hz.
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