In this paper, the influence of foam filling of aluminum honeycomb core on its in-plane crushing properties is investigated. An aluminum honeycomb core and a polyurethane foam with densities of 65, 90, and 145 kg/m 3 were used to produce foam filled honeycomb panels, and then experimental quasi-static compression tests were performed. Moreover, finite element model, based on the conducted tests, was developed. In the finite element analyses, three different polyurethane foams were used to fill three different honeycomb cores. The effects of foam filling of aluminum honeycomb core on its in-plane mechanical properties (such as mean crushing strength, absorbed energy, and specific absorbed energy) were analyzed experimentally and numerically. The results showed that the foam filling of honeycomb core can increase the in plane crushing strength up to 208 times, and its specific absorbed energy up to 20 times. However, it was found that the effect of foam filling decreases in heavier honeycombs, producing an increment of the above mentioned properties only up to 36 and 6 times, respectively.

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The stiffness of arterial wall in response to cardiovascular diseases has been associated with the changes in extracellular matrix (ECM) proteins, i.e., collagen and elastin. Vascular smooth muscle cells (VSMCs) helped to regulate the ECM reorganizations and thus contributed to arterial stiffness. This article reviewed experimental and computational studies for quantifying the roles of ECM proteins and VSMCs in mechanical properties of arteries, including nanostructure and mechanical properties of VSMCs and ECMs, cell-ECM interaction, and biomimetic gels/scaffolds induced contractile properties and phenotype changing of VSMCs. This work will facilitate our understanding of how the microenvironments and mechanotransduction impact and regulate the arterial adaptation.

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The honeycomb sandwiches are widely used in the transportation engineering for the realization of lightweight and crashworthy structures. However their application requires a better understanding of their impact response. Aims of this paper are the numerical investigation of aluminium honeycomb sandwiches subjected to low-velocity impact tests and the validation of finite element (FE) results. Before and after the low-velocity impact tests at different velocities, three dimensional (3D) reconstructions of the honeycomb panels have been carried out by a computed tomographic system in order to acquire exactly the dimension and the shape of the damage and to obtain information about geometry and cells defects. The FE models have been computed from CT data of the undamaged panels. The direct comparison has been done by superimposing the deformed images obtained from FE analyses and from 3D CT space reconstructions. The numerical model was also validated comparing the FE results with experimental data.

Abusive head trauma (AHT) is the leading cause of infant death and long-term morbidity from injury. The ocular consequences of AHT are controversial, and the pathophysiology of retinal research findings is still not clearly understood. It has been postulated that vitreoretinal traction plays a major role in the retinal findings. A computer simulation model was developed to evaluate the vitreoretinal traction and determine whether the distribution of forces in different layers and locations of the retina can explain the patterns of retinal hemorrhage (RH) seen in AHT.DESIGN: Computer simulation model study. METHODS: A computer simulation model of the pediatric eye was developed to evaluate preretinal, intraretinal, and subretinal stresses during repetitive shaking. This model was also used to examine the forces applied to various segments along blood vessels.RESULTS: Calculated stress values from the computer simulation ranged from 3-16 kPa at the vitreoretinal interface through a cycle of shaking. Maximal stress was observed at the periphery of the retina, corresponding to areas of multiple vessel bifurcations, followed by the posterior pole of the retina. Stress values were similar throughout all 3 layers of the retina (preretinal, intraretinal, and subretinal layers).CONCLUSIONS: Ocular manifestations from AHT revealed unique retinal characteristics. The model predicted stress patterns consistent with the diffuse retinal hemorrhages (RH) typically found in the posterior pole and around the peripheral retina in AHT. This computer model demonstrated that similar stress forces were produced in different layers of the retina, consistent with the finding that retinal hemorrhages are often found in multiple layers of the retina. These data can help explain the RH patterns commonly found in

The mechanical advantage of the flared stent was unveiled by the significantly increased contact force, which provided the anchoring effect to resist stent migration. Both the strut diameter and friction coefficient positively correlated with the migration resistance force, and thus the occurrence of stent migration.