Background:Ochratoxins belong to a group of mycotoxins produced as the secondary metabolites by filamentous fungi, such as Aspergillus and Penicillium. These toxins may be teratogenic, mutagenic, hepatotoxic, nephrotoxic, and may have immunosuppressive effects and pose a serious health problems to exposed humans and animals.Objectives:The present study aimed to determine the level of ochratoxin A (OTA) in the samples of mothers' milk in the Khorrambid Town, Fars Province, south of Iran.Materials and Methods:Between June and July 2011, samples of human milk were obtained from 87 mothers. The samples were diluted by absolute methanol at 1:4 ratio and after centrifugation, the supernatant was directly used to determine the level of OTA using competitive enzyme-linked immunosorbent assay (ELISA).Results:Among 87 human milk samples, 84 (96.6%) samples had positive results for OTA at a mean level of 24.57 ± 13.6 ng/L. According to the European Union Standard, 14 (16%) positive samples revealed more than the maximum limit of 40 ng/L for ochratoxin (range, 1.6-60 ng/L).Conclusions:Presence of OTA in the milk of mothers denotes a probable consumption of a contaminated foods. Therefore, regular monitoring of foods for presence of mycotoxins for lactating mothers seems necessary.
Background: The importance of preserving and maintaining printed materials is crucial for the libraries. Fungi play the main role in destroying wood and paper. Objectives: This research aimed to study and identify threatening fungal agents of library resources in Isfahan University of Medical Sciences. Materials and Methods: This is a descriptive analytical study. 126 samples were collected and examined for the presence of fungi. An open plate method was used to scan airborne fungal contents and triplicate samples were collected at four different locations in the morning, at noon, and in the evening. The fungal culture media were incubated at 25-30 ºC until growth appeared and then the fungi colonies were identified by routine mycological laboratory methods. Results: 1265 colonies of fungi belonging to 26 genera were identified in the air and different surfaces of books (references and circulation departments) and also surfaces of shelves in libraries. Cladosporium sp., Penicillium sp., Aspergillus sp. and Alternaria sp. were the most common isolated fungi in libraries of Isfahan University of medical sciences. Conclusions: We suggest training librarians as one of the most important steps in libraries to preserve library materials because having no knowledge about threatening factors and the way to fight with them are the main reasons of most frequent damages to library resources. Using new methods and technologies of preserving and maintenance of materials should be a priority in library managers' planning.
Introduction:Aflatoxins are secondary toxic metabolites produced by certain group of Aspergillus species in suitable conditions. These toxins are highly toxic, immunosuppressive, mutagenic, teratogenic and carcinogenic metabolites. The purpose of this study was to detection aflatoxin M1 concentration in mother's milk from rural area of Khorrambid town of Fars Province.Materials and Methods:In this study, 87 milk samples of mothers were collected by cluster sampling methods in the period between June and July 2011 and the amount of aflatoxin M1 was measured by a competitive ELISA method.Results:From 87 mother's milk, 24 (27.6%) samples were contaminated with aflatoxin M1 with mean concentration of 0.56 ± 1.23 pg/ml (range 0.13-4.91 pg/ml).Conclusion:The amount of aflatoxin M1 in mothers’ milk was lower than 50 ng/l (Europe Union and Iranian standard). Detection of Aflatoxin M1 in mothers’ milk is due to consuming contaminated food. This contamination not only threatens the health of the mothers but also has irreversible effects on the growth and health of their babies.
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