ST-segment elevation myocardial infarction results from acute occlusion of a coronary artery. Mortality is high in this acute coronary syndrome. Mechanical reperfusion by primary percutaneous coronary intervention (PCI) is the most effective method to restore coronary circulation. The ultimate goal of primary PCI is successful myocardial reperfusion. Thrombus aspiration (TA) using manual TA catheters has been reported to improve coronary and myocardial circulation. This, however, does not translate into long-term mortality benefit and may be associated with an increased risk of stroke. This article reviews the role of TA as an adjunct to mechanical reperfusion during PCI.
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