Excavations at two sites dating from BC-1900

In this study, the fabrication method was proposed for the well-interconnected polycaprolactone/hydroxyapatite composite scaffold with exposed hydroxyapatite using modified WNM technique. To characterize well-interconnected scaffolds in terms of hydroxyapatite exposure, several assessments were performed as follows: morphology, mechanical property, wettability, calcium ion release, and cell response assessments. The results of these assessments were compared with those of control scaffolds which were fabricated by precision extruding deposition (PED) apparatus. The control PED scaffolds have interconnected pores with nonexposed hydroxyapatite. Consequently, cell attachment of proposed WNM scaffold was improved by increased hydrophilicity and surface roughness of scaffold surface resulting from the exposure of hydroxyapatite particles and fabrication process using powders. Moreover, cell proliferation and differentiation of WNM scaffold were increased, because the exposure of hydroxyapatite particles may enhance cell adhesion and calcium ion release. © 2016 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 105B: 2315-2325, 2017.

We fabricated a 3D knee joint model through the imaging processing. The 3D shape information is different depends on specific conditions when the shape of real knee joint is extracted from CT/MRI sliced images. The two types of joint models were fabricated by using 3D printer in order to analysis of joint movement by slight difference of 3D shape information. The compressive force experiments were performed by using knee joint model. As the results, the compressive forces were changed with respect to the difference of geometry. Consequently, feasibility test should be performed before developing biomimetic bioreactor.

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