Background: The lack of knowledge of the biochemical processes in the treatment process of Lutuku constitutes a real problem. The study compares the enzymatic activity of transaminases in consumers of native Lutuku alcohol and non-consumers.Methods: This is a case-control study involving 40 Lutuku-consuming and healthy subjects. The enzymatic activities of GOT and GTP were performed using standard clinical chemical methods developed by BIOLAB.Results: The rate of TGO and TGP are 4 to 5 times higher in consumers of Lutuku than in healthy subjects. In the control group, the median TGO/TGP serum ratio was more pronounced in women (0.9667 U/l) than in men (0.88 U/l). Female alcoholics had a serum TGO/TGP ratio of 1, while males had a median ratio of 1.0275. Serum GOT/GTP ratios were correlated with serum GOT in both sex with respectively (r = 0.268 , p < 0.01) in men and (r= 0.499, p < 0.05) in women; and GTP (r = 0.236 , p < 0.01 ) only in men.Conclusion: Consumption of Lutuku induced four to five times more transaminase activities (TGO and TGP) compared to those observed in healthy.
Introduction. HIV/AIDS continue to be serious communicable disease whose impact on public health in Namibia is massive. It is estimated that the prevalence rate of HIV in Namibia is 17.2%, ranking the country as the fifth highest in sub-Saharan Africa (SSA). Some improvement in reducing the number of cases of HIV/AIDS has been made in the country, but the sporadic shortage of medicines continues to slow down government efforts to foster the emergence of an HIV-free generation of Namibians Objective of the study. Develop and demonstrate a mathematical supply-chain model, which can establish parameters to prevent stock-outs of NVP suspension. Method: The study adopted retrospective approach to acquire data from 2012-2016. Results. Gamma supply chain model was developed as the optimal model for NVP syrup and forecasted consumption for 2017-2018 was determined. Conclusion and recommendation. It is a recommendation of this study that new guidelines for implementation of optimal supply-chain models at the regional medical store, health centers and clinics be implemented for Nevirapine syrup.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.