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Four Yucaipa-like viruses of avian paramyxovirus serotype 2 (APMV-2) were isolated in China from the imported Gouldian Finch (Chloebia gouldiae) and broilers in 1998-2002, and were named F4, F6, F8, and NK, respectively. Examined under electron microscope, the isolates were found to be round in shape and varying in size. The results of the hemagglutination inhibition test and indirect enzyme-linked immunosorbent assay (using monoclonal antibodies) showed some differences between the isolates and the reference strain Yucaipa. The isolates derived from chickens had a closer relationship to Yucaipa virus than did those of finches. Sequence comparison of the fusion gene and the haemagglutinin-neuraminidase gene showed similar results, although the variations were lesser among APMV-2 viruses in nucleotide and amino acid sequence. By sequence comparison, it was also revealed that at the molecular level the four virus strains belong to APMV-2, and that two of the strains were isolated from the same group of imported Gouldian Finches.

Background:In recent years, the problem-based learning (PBL) teaching method has been extensively applied as an experimental educational method in Chinese radiology education. However, the results of individual studies were inconsistent and inconclusive. A meta-analysis was performed to evaluate the effects of PBL on radiology education in China.Methods:Databases of Chinese and English languages were searched from inception up to November 2017. The standard mean difference (SMD) with its 95% confidence interval (95% CI) was used to determine the over effects of PBL compared with the traditional teaching method.Results:Seventeen studies involving 1487 participants were included in this meta-analysis. Of them, 16 studies provided sufficient data for the pooled analysis and showed that PBL teaching method had a positive effect on achieving higher theoretical scores compared with the traditional teaching method (SMD = 1.20, 95% CI [0.68, 1.71]). Thirteen studies provided sufficient data on skill scores, and a significant difference in favor of PBL was also observed (SMD = 2.10, 95% CI [1.38, 2.83]). Questionnaire surveys were applied in most of the included studies and indicated positive effects of PBL on students’ learning interest, scope of knowledge, team spirit, and oral expression.Conclusion:The result shows that PBL appears to be more effective on radiology education than traditional teaching method in China. However, the heterogeneity of the included studies cannot be neglected. Further well-designed studies about this topic are needed to confirm the above findings.

To analyze the source characteristics of the 2016-2017 central Italy seismic sequence, source spectra of 78 earthquakes of M L = 3.5-6.1 were separated from the S wave Fourier spectra using the two-step nonparametric generalized inversion technique. Source parameters (e.g., stress drop) were estimated from the source spectra following the ω-square model. Stress drops were found mainly in the range 0. 113-12.190 MPa. The significant dependence of stress drop on magnitude indicates the breakdown of earthquake self-similar scaling in this sequence. The low stress drops for small events following the release of high stress by the mainshock might have led to stress accumulation on the unruptured fault, which could explain the subsequent occurrence of multiple major events. We investigated the source rupture directivity for 36 events through the azimuthal variation of apparent source spectra. Significant variation was observed at specific frequency bands (generally, over corner frequencies) in 10 events caused by rupture directivity, which was verified by the stable estimation of rupture plane. The rupture parameters confirmed unilateral ruptures predominantly on the NNW-SSE striking fault with fast rupture velocity (2.52-2.84 km/s) for the 10 events. Rupture parameters for an additional four events with stable estimated rupture plane were also analyzed. These were characterized by slow rupture velocity causing weak directivity effects. According to the rupture parameters for the 14 events, prevailing SSE or SEE (NNW or NNE) rupture directivity was a common feature for events to the north (south) of the mainshock in this earthquake sequence.

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